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Actalipid (Simvastatin)
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Actalipid

Actalipid is a cholesterol-lowering medication which used to treat high cholesterol levels in the blood. It works by blocking the production of cholesterol in the body. It can help prevent conditions that can lead to heart attack, heart disease and hardening of the arteries, stroke, and vascular disease. This medication can also reduce these risks in people with diabetes, peripheral vascular disease, and a history of stroke. Use this medication during low fat diet to get the best result.

Other names for this medication:
Actalipid, Docsimvasta, Dosavastatin, Lipex, Lipinorm, Lodales, Normotherin, Simbastatin, Simgal, Simvastatin, Simvastatina, Simvastatinum, Simvofix, Sinvacor, Sivastin, Statinal, Vasilip, Zocord, Zorced, Zorstat, Zosta, Zostin, Zostine, Zovast, Zovastin, Zovatin, Zurocid

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Also known as: Simvastatin

Description

Actalipid (simvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

Actalipid is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Actalipid is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.

Actalipid is used in adults and children who are at least 10 years old.

Dosage

Take Actalipid exactly as prescribed. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medication may cause serious or life-threatening side effects.

Actalipid is usually taken at bedtime or with an evening meal. If you take this medicine more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results.

While using Actalipid, you may need frequent blood tests at your doctor's office.

You may need to take Actalipid on a long-term basis for the treatment of high cholesterol. You may need to stop using this medicine for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.

Actalipid is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Actalipid dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actalipid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Actalipid if you are allergic to Actalipid components. Be careful with Actalipid if you're pregnant or you plan to have a baby. Do not use it if you are a nursing mother. Be careful with Actalipid if you suffer from low blood pressure, kidney problems, diabetes, serious infection, metabolism problems, hormonal problems. Do not use potassium supplements or salt substitutes. Avoid eating grapefruit or drinking grapefruit juice while taking Actalipid. While taking Actalipid, you can make laboratory tests (blood cholesterol levels, liver function tests, creatine phosphokinase blood levels) to monitor the condition of your health. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Be very careful when you are driving machine. Do not stop taking Actalipid suddenly.

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The solvent influence on the positional selectivity of Novozym 435 during 1,3-diolein synthesis by esterification. The role of endotoxin in the inflammatory response syndrome has been well investigated. Impact of lateral pelvic lymph node dissection on evacuatory and urinary functions following low anterior resection for advanced rectal carcinoma. Gender differences have been described in major mental illnesses (MMI). Geographic regions in the highest and lowest deciles of intensive care unit (ICU) use. PLS revealed that emollient sensory attributes could be well predicted by instrumental measurements. Imaging functional neural circuits in zebrafish with a new GCaMP and the Gal4FF-UAS system. Politicians and tobacco control in New Zealand: a brief three-year audit. Certain conformations of a receptor bind the anesthetic with greater affinity than others. Molecular evolution analysis and geographic investigation of severe acute respiratory syndrome coronavirus-like virus in palm civets at an animal market and on farms.

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Selective inhibition of hepatic gluconeogenesis gy tryptophan administration. The objective of this study was to evaluate a new blood pool contrast agent, B-22956, for detecting myocardial perfusion abnormality and coronary artery stenosis by magnetic resonance imaging (MRI) in 1 setting. The ability to measure glucose noninvasively in human subjects is a major objective for many research groups. We have developed a rapid, reliable, and sensitive quantitative flow cytometric assay to measure the in vitro potency and stability of DNA vaccines to be delivered either by particle-mediated epidermal delivery (PMED) or by electroporation. Using an enzyme-linked immunosorbent assay (ELISA) sera from 100 individuals, 20 with motor neuron disease (MND), 25 with peripheral neuropathy (PN), 15 with degenerative dementia and 40 controls, were examined in order to detect serum IgM and IgG anti-GM1 and anti-GD1a antibodies. Chromosome congression and segregation have been widely known to be coordinated by the function of the dynamic spindle microtubules. This protein was a potent inhibitor of the papain and of the major cysteine protease of F. diabolica, which appeared to be related only to areas of occasional transmission in northern Mexico. Vocal fold injection: review of indications, techniques, and materials for augmentation. Influence of systolic intracavity pressure on right ventricular perfusion in the awake dog.

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Recording diaphragm activity by an oesophageal probe: a new tool to evaluate the recovery of diaphragmatic paralysis. In a system in which unphagocytosed bacteria were removed by differential centrifugation after a 30-min phagocytosis period, staphylococci associated with rabbit polymorphonulcear (PMN) leukocytes were completely protected from the effects of benzyl penicillin 1 microgram/ml, but not completely protected from the effects of 5 micrograms/ml. Lenalidomide was well tolerated in intensively pretreated and elderly MM patients, including those with RI. Mycobacterium tuberculosis (MTB) is a major cause of morbidity and mortality in the world. Analysis of the extension of Q-waves after infarction with body surface map: relationship with infarct size. Preparation, assay, and partial characterization of a neutral endopeptidase from rabbit brain.

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Pegylated liposomal doxorubicin as first-line monotherapy in elderly women with locally advanced or metastatic breast cancer: novel treatment predictive factors identified. Preexposure of rabbits to Mycoplasma arthritidis predisposed them to subsequent development of chronic inflammation in knee joints challenged with nonviable M arthritidis antigens. Blockbusters and controlled substances: Miltown, Quaalude, and consumer demand for drugs in postwar America. To clarify amaryl drug class causation, this study aims to assess whether prolonged crying at 5-6 weeks (the peak age for crying) predicts which infants are unsettled in the night at 12 weeks of age (when most infants become settled at night). However, the role of PrC in unitization processes remains unclear.

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Previous studies have found an association between bruxism and emotional and behavioral problems in children, but reported data are inconsistent. Here, we demonstrate that CD147 carries sorting information for polarized targeting of the MCT1/CD147 hetero-complexes in kidney and RPE cells. The results support the importance of screening needs and psychological distress among family members of cancer patients in all phases of illness. Treatment of the 38 patients with multiple aneurysms is described. An evaluation of the gas chromatographic estimation of trace quantities of hexachlorophane. The HGF/MET pathway as target for the treatment of multiple myeloma and B-cell lymphomas. Peroxidative stress effects on calpain activity in brain of young and adult rats. Effects of luteectomy and progesterone replacement therapy in early pregnant patients. A tunable diode laser was used for absorption tomography in an axisymmetric atmospheric pressure flat-flame burner. This injury can trigger a systemic inflammatory syndrome, also producing remote organ damage.

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Clinical features of the dilated phase of hypertrophic cardiomyopathy in comparison with those of dilated cardiomyopathy. Likewise, blocking the IL-1 type 1 receptor by addition of IL-receptor antagonist (IL-1ra) significantly enhanced LOS-mediated caspase-3 activation. In five joints the grafted cartilage included osseous portions using the costo-osteochondral junction, leading to an average range of movement of 64 degrees with satisfactory clinical results. Microsynteny was found between the region on N7 carrying the resistance gene motrin medication and the end of Arabidopsis chromosome 1, interrupted by a single inversion close to the resistance locus. Cellular immunotherapies offer perhaps the best proof of concept of the ability of immune cells to eradicate malignancy. This review addresses three questions regarding the relationships among gender, emotion regulation, and psychopathology: (a) are there gender differences in emotion regulation strategies, (b) are emotion regulation strategies similarly related to psychopathology in men and women, and (c) do gender differences in emotion regulation strategies account for gender differences in psychopathology?. Reconstitution of monocyte-depleted cultures with autologous monocytes partially corrected the diminished response to antigens. Angiotensin II (AngII) is the biologically active peptide of the renin-angiotensin system (RAS). A 15-year-old boy experienced a rapidly enlarging nodule on his left nose. However, there are some concerns about the intravitreal ICG application.

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A membrane protease regulates energy production in macrophages by activating hypoxia-inducible factor-1 via a non-proteolytic mechanism. The literature was systematically reviewed to determine whether a prolonged prothrombin time or elevated international normalized ratio predicts bleeding during invasive diagnostic procedures. Physical studies of chloroacetaldehyde labelled fluorescent DNA. The results suggest a link between cortical motion adaptation and adaptive mechanisms effecting the oculomotor system. The effects of fluoxetine in male rats were not potentiated by T3. Reading acuity (LogRAD) and reading speed were determined with the standardized Radner reading charts. The auditory bulla in Carnivora: an anatomical basis for reappraisal of carnivor evolution. Introduction of the emm6 gene into an emm-deleted strain of Streptococcus pyogenes restores its ability to resist phagocytosis. The safety and efficacy of an exclusively systemic application of GM-CSF in patients with coronary artery disease (CAD) and collateral artery promotion has not been studied so far. Plasma levels of D-dimer, but not SF, correlated significantly with plasmin plasmin inhibitor complex (PPIC).

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