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Actocard (Metoprolol)

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Actocard is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. Actocard among others, is a selective β₁ receptor blocker medication.

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Also known as: Metoprolol


Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. A lower blood pressure can reduce the risk of strokes and heart attacks.

Metoprolol is also used to treat severe chest pain (angina) and lowers the risk of repeated heart attacks. It is given to people who have already had a heart attack. In addition, metoprolol is used to treat patients with heart failure.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take Actocard HCT with or without food.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, or heavy sweating. Call your doctor if you are sick with vomiting or diarrhea.

Your blood pressure will need to be checked often. You may also need frequent blood tests.

If you are diabetic, check your blood sugar carefully. Taking Actocard HCT can make it harder for you to tell when you have low blood sugar. Do not change your medication dose or schedule without your doctor's advice.

If you need surgery, tell the surgeon ahead of time that you are using Actocard HCT.

Keep using Actocard HCT as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Do not stop using Actocard HCT suddenly, even if you feel fine. Stopping suddenly may cause serious or life-threatening heart problems. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture and heat.

Detailed Actocard HCT dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast or slow heart rate, trouble breathing, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actocard are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Actocard if you are allergic to Actocard components. Do not take Actocard if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Actocard if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Actocard in case of taking cimetidine (Tagamet), clonidine (Catapres), diphenhydramine (Benadryl), fluoxetine (Prozac, Sarafem), hydroxychloroquine, paroxetine (Paxil), propafenone (Rythmol), quinidine (Quinaglute, Quinidex), ranitidine (Zantac), reserpine (Serpalan, Serpasil, Serpatab), ritonavir (Norvir), terbinafine (Lamisil),and thioridazine (Mellaril), bupropion (Wellbutrin). Be careful with Actocard if you have allergies to medicines, foods, or other substances. Be careful with Actocard if you suffer from or have a history of heart or liver disease; diabetes; severe allergies; or an overactive thyroid gland (hyperthyroidism), slow heart rate, heart failure, problems with blood circulation, or pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heartbeat), had asthma or other lung disease. Use Actocard with great care in case you want to undergo an operation (dental or any other). Avoid alcohol. Avoid machine driving. Do not stop taking Actocard suddenly.

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We discuss how the changes in the rate of slow transport may reflect different neuronal responses to injury and speculate about the possible molecular changes in the expression of tubulin which may contribute to the observed changes. The study provides the first objective evidence that Prader-Willi syndrome patients indeed have developmental abnormalities in specific areas of the brain, providing a new window toward understanding the pathophysiology of Prader-Willi syndrome. Considerations on a case of pulmonary hyper-flow caused by congenital cardiopathy with long survival. Dynamic modulation of baroreflex sensitivity in health and disease. The recombinant neelaredoxin has spectroscopic properties identical to those observed for the native one. Predicting phase steps in phase-shifting interferometry in the presence of noise and harmonics. Nitroimidazole adducts as markers for tissue hypoxia: mechanistic studies in aerobic normal tissues and tumour cells. The primary causes of ED were determined by comprehensive diagnostic procedures in the urology/andrology clinics in five training hospitals. Porcine reproductive and respiratory syndrome (PRRS): an immune dysregulatory pandemic.

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Bipolar spectrum disorder: improving its recognition and diagnosis. Sleep disordered breathing, fatigue, and sleepiness in HIV-infected and -uninfected men. IL-2Ralpha and IL-2Rbeta, respectively, are markers for double-negative thymocytes and regulatory T-cells versus memory cells. Information regarding the age, signs of cerebral herniation, haematoma volume, intra-ventricular haemorrhage, intra-cerebral haemorrhage score and the treatments of each patient were analyzed retrospectively. It is shown that the decrease in Tmax and the narrowing of the heat absorption peak in the case of decreasing heating rates of protein solutions, observed under certain environmental conditions, results from the irreversibility of the denaturation process. Clinical diagnosis and classification with respect to early prognosis and treatment. Results indicated significant improvement in PTSD-associated insomnia, nightmares, PTSD symptoms, and Global Assessment of Functioning and subjective improvement in chronic pain.

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PriB stimulates PriA helicase activity via interaction with single-stranded DNA (ssDNA), but the molecular details of this interaction remain unclear. Extensive myelin swelling and axonolysis were observed in the rats killed 1 and 2 weeks after glycerol injection. The design and implementation of COSEM, an iterative algorithm for fully 3-D listmode data. Monoclonal antibody to human esophageal cancer endothelium inhibits angiogenesis and tumor growth. The new triazole agents, voriconazole and posaconazole, have a broad spectrum of antifungal activity. Four spirochetal isolates (JEM1 to JEM4) were obtained from cutaneous lesions of patients manifesting erythema chronicum migrans in Hokkaido, Japan. Based on a concept that all ocular artifact components exist in a signal component subspace, the method can uniformly handle all types of ocular artifacts, including eye-blinks, saccades, and other eye movements, by automatically identifying ocular components from decomposed signal components. Notably, 9a at 300 mg/kg (i.p.) showed no overt toxicity in contrast to 1 (LD50 56.2 mg/kg, i.p.) and 3 (LD50 177.5 mg/kg, i.p.). Physical examination, electrocardiography, coronary angiography.

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Liquid paraffin: a reappraisal of its role in the treatment of constipation. This review summarizes patent applications in the past 5 years for the management of brain tumors and metastases. Somatic cross-sectional areas vary between 140 microns2 and 440 microns2. Because X-rays induce switching immediately after irradiation and because the DNA double-strand break repair pathway is required for switching, the event initiating heterothallic mating type switching is likely to be a DNA double-strand break. During assembly of HIV-1 particles in infected cells, the viral Pr55(Gag) protein (or Gag precursor) must select the viral genomic RNA (gRNA) from a variety of cellular and viral spliced RNAs. The MTF, NNPS, and DQE are standard linear system metrics used to characterize intrinsic detector performance. For this study, T1-T6 vertebrae from 503 American human cadavers were directly measured with a digital caliper. In particular, DNA has proven to be one of the most versatile and robust building blocks for construction of complex three-dimensional architectures with high fidelity. The relation between food intake and abomasal emptying and small intestinal transit time in sheep. Evidence for the link between healing time and the development of hypertrophic scars (HTS) in paediatric burns due to scald injury.

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A comparison of the degree of alkylation of plasma proteins, hemoglobin and guanine-N-7 in DNA suggests that the two compounds are about equally effective as alkylating agents in vivo at moderate dose levels. (20 mg) on pulmonary hypertension following chronic obstructive pulmonary disease (COPD) and advanced pulmonary fibrosis (PF) have been studied in 6 patients under stable conditions (3 patients with COPD and 3 patients with PF). A small group of all-trans retinoic acid (tRA)-inducible genes had lower transcript levels in GFP-3a1Nter cells than in wild-type mESCs. The allopurinol-induced change in the antitumor activity of cyclophosphamide as seen in the spleen colony assay was not explainable on the pharmacokinetic basis. Sixty to 70 per cent of the individuals who are running regularly are injured severely enough that they must temporarily stop running.

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Absence of the action of choline on the parasympathetic ganglia of the cardiac pneumogastric nerve. It is concluded that rapid chloride tests designed for water analysis might be suitable to determine NaCl in urine samples. Radiotherapy of hydrocephalus in meningeal tuberculosis treated with streptomycin. In concert with increased frequencies of other growth issues in such cases, such as side differences in size and morphology, hypodontia is best viewed as a symptom of an anatomically broad relaxation of developmental canalization between homologous structures, not an isolated dental feature. Amplatzing a 6 Fr Judkins right guiding catheter for increased success in complex right coronary artery anatomy. Identification and characterization of COI1-dependent transcription factor genes involved in JA-mediated response to wounding in Arabidopsis plants.

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The physiological disposition of probenecid, including renal clearance, in man, studied by an improved method for its estimation in biological material. Hyperornithinaemia is accompanied by lysinuria and reduced lysine plasma levels in GA. We recommend governments use three types of lists: (1) threatened species lists constructed following a sound categorization system, (2) lists of species of conservation priority, and (3) lists that serve as normative tools (e.g., Convention can you buy ventolin over the counter in ireland on International Trade in Endangered Species of Wild Fauna and Flora). Using the overdispersed exponential family to estimate the distribution of usual daily intakes of people aged between 18 and 28 in Taiwan. These results suggest that exposure to novel environmental stimuli may reduce acquisition of drug-taking behavior, especially among high-novelty-seeking individuals.

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This enzyme catalyses the conversion of methionine to S-adenosylmethionine (SAM), the major methyl group donor in living cells. Registration number NCT02046967 ( Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms. We aimed to study the role of DNA methylation as an inducer of HOX gene silencing in leukemia. The high rate oftransmission for water can be correlated with the thickness of the dense layer on the air-driedsurface of aceon ignition coil reviews the membrane. Degenerative changes including loss of inner and outer hair cells were seen at P20, with severe sensory cell loss in all cochlear turns occurring by P40. The first two groups were further divided into subgroups on the basis of their exposure to radioactivity at 37, 55.5, or 74 kBq/mL, with the saline-exposed group divided into three corresponding subgroups.

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Solid phase solubility is a fundamental parameter in the design of crystallization processes. The concentration of the parent drug and its major metabolite nortriptyline in plasma were measured by high performance liquid chromatography. Our study identified 45 321 tags that match the antisense strand of 9804 known mRNA sequences, 6606 of which contain antisense ESTs and 3198 are mapped only by SAGE tags. Phylogenetics of cytoplasmically inherited microorganisms of arthropods. Breeding experiments show that sex ratio variation in this species is primarily maternally inherited and that removal of the bacteria by antibiotics restores an unbiased sex ratio. Patterns of needle acquisition and sociobehavioral correlates of needle exchange program attendance in Baltimore, Maryland, U.S.A. Accessing long-term memory representations during visual change detection. This paper describes the use of epiglottis in repair of laryngeal and tracheal defects due to cancer or trauma.

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Unusual radiological image at the level of the right lumbar course of the ureter. Analytical control of molecular excitations including strong field polarization effects. A case of acute encephalopathy with posterior corticosubcortical vasogenic edema on magnetic resonance imaging is reported. Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. In black young adults, genetic risk scores constructed using loci identified in European and African American samples had similar predictive power.

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This action not only explains the seemingly contradictory cause of Smith-Lemli-Opitz syndrome (SLOS), but also establishes Hh as a unique morphogen, because binding of Hh on one cell is capable of activating Hh-dependent signalling cascades on other cells. Complete control of disease occurred in nine patients, partial control (as evidenced by my ability to lower the corticosteroid dosage) was obtained in three patients, and one patient had no demonstrable effects during a 1-month period of colchicine therapy. Clinical and prognostic significance of histamine monitoring in patients with CML during treatment with imatinib (STI571). Histology corroborated a lower degree of inflammatory lesions and demyelination in the sciatic nerve. Fundamental questions about the nature of these unique host-microbe interactions also remain unanswered. On the problem of formation of the extensor muscle of the small finger, M.

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eComment: Endovascular treatment of chronic aortic dissection: is an uncovered stent the way to go?. A priority should be given first for collecting and recording indigenous knowledge from the natives inhabiting the national parks and environmental preservation areas. Adequate micronutrient intake throughout life course is essential for the maintenance of health. Further, different water levels in restored habitats are likely to determine its species composition of the plant community. The enamel loss was measured using a confocal laser scanning microscope. The Fourier-domain ratio of these oscillations in pressure and flow constitutes what we call cardiogenic respiratory impedance (Zc). Chikungunya virus (CHIKV) represents a threat to the United States, because humans amplify CHIKV and vectors that transmit CHIKV are present.

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CD44 has been implicated to play an important role in a diverse range of physiological processes, which involve cell-matrix recognition, cell-cell adhesion and cell motility. The results promote adjustment of theoretical probability distributions for age groups, combining workers of all plants in all age groups excluding the youngest, i.e. On the relation of the character and duration of a pulmonary tuberculous infection to the pathogenesis of amyloidosis. Finally, we discuss the first successful synthetic biology approaches that resulted in chloroplasts in which electrons from the photosynthetic light reactions are fed to enzymes derived from secondary metabolism. IFN-gamma-bearing cells were widespread in the connective tissue and their number increased significantly with the severity of inflammation and an increase of PD. Subcutaneous immunization of rabbits with a combination of Vibrio cholerae lipopolysaccharide (LPS) and enterotoxin induced a more than 100-fold-higher degree of protection against intestinal challenge with live cholera vibrios than did vaccination with either of the two antigens alone. The preoperative sum total range of motion was maintained astelin eye drops dosage or improved in hips with a painful arc of motion. While structural changes can be identified which might enhance the consumer role in decision making, it will also be necessary for the consumer sector to develop a strategy which will prompt major rather than incremental movement. 1-octen-3-ol isolated from bont ticks attracts Amblyomma variegatum. As the gap between the tip of the valve occluder and orifice wall becomes narrower, evidence of high-speed jet flow becomes more apparent.

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Radiographic examination of this tooth showed resolution of the periapical lesion, further root development, and continued apical closure. In the field study, cats were treated with three intramuscular injections of 1 ml vaccine administered at 14-day intervals, as recommended by the manufacturer. Three positive cell lines were identified and cloned by limiting dilution. Data from 67 pig farms with a variety of farrowing systems were used to identify factors associated with preweaning mortality in British pig herds. Indeed, several independent miRNA profiling studies reported significant differences between SLE patients and healthy controls. The aim of the systematic review was to identify, explore and evaluate the current level of knowledge of methodologies used in comparative analyses of the individual practice of doctors, nurses and midwives. Patients, FDA and drug companies struggle to link therapies with well-being.

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Further inspection of the behavior of these interstitial H(2)O molecules has revealed that they are relatively highly mobile entities within a gas hydrate. This suggests that using the amiloride hcl 5 mg side effects FD2, distance stereoacuity in intermittent exotropia is either absent or normal rather than reduced. G-CSF improved functional recovery in spontaneously hypertensive rats, but this effect was abolished by cotransplantation of BM MNC after 48 hours. Heating of materials by a powerful focused laser beam for the purpose of study of vapor fractionation is a convenient technique that is more versatile than previous methods such as heating in solar or arc image furnaces. Chromosomal mosaicism in spontaneous abortions: analysis of 650 cases. To minimize the risk of supratherapeutic INR values and/or hemorrhagic events, clinicians should perform serial monitoring of INR when initiating fenofibrate therapy in a patient previously stabilized on a coumarin anticoagulant. This device monitors the gas pressure in a CO2 incubator gas system and automatically switches to a reserve tank when the main supply tank is depleted.

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