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Agiclob (Clobetasol)

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Agiclob is effective in treating allergic skin conditions with inflammation and itching such as eczema and dermatitis. It works by reducing the actions of chemicals in the body that cause inflammation of the skin.

Other names for this medication:
Betalic, Clobadis, Clobate, Clobecos, Clobesym, Clobet, Clobetamil, Clobetasol, Clobevate, Clobex, Clobin, Clomad, Clomax, Cloriv, Cosvate, Covate, Cutivate, Eavone, Embeline, Gracederm, Hinate, Isovate, Klosol, Magclo, Miconit, Monosol, Salyco, Steriderm, Steridom, Taxalic, Tenovate, Topisal, Zincoderm

Similar Products:
Cipro, Nolvadex, Norvasc, Lasix, Phenergan, Zudena, Sanigst, Promegan, Macorel, Oxcazo, Simgal, Clominova, Cefaclor, Clopod, Jbcloz,

Also known as: Clobetasol


Generic Agiclob is an effective topical (applied to the skin) corticosteroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling. Generic Agiclob is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Generic Agiclob is also used to treat moderate to severe psoriasis. Generic Agiclob may also be used for other purposes. Generic name of Generic Agiclob is Clobetasol. Brand names of Generic Agiclob are Clobevate, Clobex, Cormax, Embeline E, Olux, Olux-E, Agiclob.


This section provides information on the proper use of a number of products that contain clobetasol. It may not be specific to Agiclob E. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

This medicine is for use on the skin only. Do not get it into your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

To help clear up your skin or scalp problem completely, it is very important that you keep using this medicine for the full time of treatment. Do not miss any doses.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor first before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

Do not use this medicine on the face, groin, or underarms, or if you have skin thinning, unless directed to do so by your doctor.

To use the cream, foam, gel, lotion, ointment, or spray:

Wash your hands with soap and water before and after using this medicine. Apply or spray a thin layer of this medicine to the affected area of the skin. Rub it in gently. With the lotion, protect the skin from water, clothing, or anything that causes rubbing until the medicine has dried. Also, shake the lotion well before using it. With the foam, do not dispense directly from the can into your hands, unless the hands are the affected area. Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor. Do not use Clobex® spray or Impoyz™ cream for more than 2 weeks unless your doctor told you to.

To use the foam, scalp solution, or shampoo:

Wash your hands with soap and water before and after using this medicine. Apply a thin layer of this medicine to the affected area of the scalp. Rub it in gently. Do not cover the scalp (eg, shower cap, bathing cap) while it is being treated. With the shampoo, do not wet your hair before using it. And if the shampoo gets on any part of your body other than your scalp, rinse the area well with water. Do not use the shampoo for more than 4 weeks, and the foam and scalp solution for more than 2 weeks unless your doctor told you to.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For redness, itching, and swelling of the skin: For topical dosage forms (cream, gel, or ointment): Adults—Apply to the affected area of the skin 2 times per day. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 12 years of age—Use is not recommended. For topical dosage form (lotion): Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. For plaque psoriasis: For topical dosage form (cream): Impoyz™: Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. Agiclob®: Adults and children older than 16 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 16 years of age—Use is not recommended. For topical dosage form (foam): Adults—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (spray): Adults—Spray directly to the affected area of the skin 2 times per day. Children—Use is not recommended. For scalp problems: For topical dosage forms (foam or scalp solution): Adults—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (shampoo): Adults—Apply to the affected area of the scalp once a day. Children—Use is not recommended.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

High doses or long-term use of Agiclob can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the foam can or spray bottle at room temperature, away from heat, flames, smoke, and direct light. Do not keep this medicine inside a car where it could be exposed to extreme heat. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Store the Agiclob® E cream at room temperature, away from heat, moisture, and direct light. Do not refrigerate. Keep Agiclob® E cream and Impoyz™cream from freezing.

Detailed Agiclob E dosage information

Side effects

The most common side effects associated with Agiclob are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of clobetasol topical cream, foam, gel, ointment, or scalp solution in children 12 years of age and older. However, because of this medicine's toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor's instructions very carefully. Safety and efficacy have not been established in children younger than 12 years of age and the use of clobetasol topical cream, foam, gel, ointment, or scalp solution is not recommended. The safety and efficacy of clobetasol topical lotion, shampoo, or spray have not been established in children and use is not recommended.

Appropriate studies have not been performed on the relationship of age to the effects of Impoyz™ cream in the pediatric population. Safety and efficacy have not been established and use in children is not recommended.


Right ventricular 3-dimensional strain in pulmonary hypertension: the quest to see the future. In this study, six different commercially available lipases are screened for activity. Other end points of interest were discontinuation due to adverse events, consent withdrawal, and nonadherence. Nicotine or placebo patch treatment began 2 weeks before a target quit date (TQD) and continued for a further 12 weeks. Effects of intraluminal pH and dietary phosphate on phosphate transport in the proximal convoluted tubule. Brain-derived neurotrophic factor (BDNF) is a survival factor for endothelial cells and expresses in the ischemic myocytes. These kinetic intermediates may be biologically important substrates for gene regulation.

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Patients experience less frequency of short-term post-obturation pain after single-visit than those having multiple-visit root canal treatment. Generation of thymotropic envelope gene recombinant virus and induction of lymphoma by ecotropic Moloney murine leukemia virus. Collagen-coated polylactide microcarriers/chitosan hydrogel composite: injectable scaffold for cartilage regeneration. A drug delivery system (DDS) consisting of lipopolysaccharide (LPS) as a drug and 2-hydroxyethyl methacrylate (HEMA)-diethylene glycol dimethacrylate (2G) or -polyethylene glycol dimethacrylate (4G, 9G) copolymer was prepared, and used for the efficient preparation of an experimental animal model of chronic hyper-endotoxemia. Investigation of the putative functions indicated that some of the proteins regulated by PACAP and identified in the present article could control cell survival or differentiation. Gastrointestinal dialysis with activated charcoal and cathartic in the treatment of adolescent intoxications. Thermometric study of the areas of fractures and of pseudarthroses. The system also allows visualization of the hyphal wall during aging, when changes from a smooth to a fissured surface are noted, and differences in adsorptive properties occur. Mangrove plants are rich sources of secondary metabolites having many beneficial biological activities including antimicrobial ones. A vacuum extractor was successfully used to elevate a depressed fracture of the parietal bone in a newborn.

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Collodion covering of the liver in the study of lymph circulation of the liver capsule. Tumefactive demyelination and a malignant course in an MS patient during and following fingolimod therapy. Eight experiments evaluated a core assumption of several theories of text processing, the shared resource assumption, which states that component text processes share limited processing resources. The occurrence of two different nucleotides at the same sequence position can be caused either by heteroplasmy or by a mix of samples. We derive a simple, generally applicable measure for the robustness of a simulated vessel against in vivo pressure fluctuations, based on quantifying the degree of synchronization between proximal and distal pressure pulses. CDK7 forms a stable complex with cyclin H and MAT1 in vivo only when phosphorylated on either one of two residues (Ser164 or Thr170) in its T-loop. The strength of the public health infrastructure determines the ability of local public health agencies to respond to emergencies and provide essential services. Serum proteins, blood and plasma volumes in experimental Trypanosoma vivax infections of sheep and goats. These analogues should be useful lead compounds for the development of novel 2-AG mimetics.

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Shared nucleotide composition biases among species and their impact on phylogenetic reconstructions of the Drosophilidae. Other aspects of near-field photodetection are also examined, including contrast mechanisms and lateral resolution. Equine herpesvirus 1 (EHV-1) is the causative agent of abortion, perinatal foal mortality, neurological and acute respiratory diseases in horses. Nevertheless, the immunity induced by the vaccine disappears in adults and cannot be boosted by readministration of BCG. We report a unique case in the literature of a 15-year-old male patient who played football and was admitted at our service complaining of sciatica radiating into the left leg. Activation of virulence in pathogenic fungi often involves differentiation processes that need the reset of the cell cycle and induction of a new morphogenetic program.

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White Americans have a 2-fold higher incidence of bladder cancer than black Americans but the latter have a higher mortality rate. The countries of the Balkan Peninsula have become the region with frequent outbreaks of the emerging and re-emerging diseases during the last decade of the 20th and the first decade of the 21st century. Penicidones A-C were the first group of natural products possessing a penicidone framework. Evidence suggests that introduction of complementary foods should not be delayed, and the diversity of the diet in early life is important. Bioluminescent systems are considered as potent reporter systems for bioanalysis since they have specific characteristics, such as relatively high quantum yields and photon emission over a wide range of colors from green to red. Mental illness stigma/discrimination was found to impact negatively on employment, income, public views about resource allocation and healthcare costs.

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One major mechanism of vascular dysfunction with IR involves the augmented generation, availability, and/or actions of reactive oxygen species (ROS). Use of the Swanson silicone trapezium implant for treatment of primary osteoarthritis : long-term results. Comprehensive assessment of DNA copy number alterations in human prostate cancers using Affymetrix 100K SNP mapping array. Inconsistent findings have been reported regarding the association between elevated plasma homocysteine (Hcy) levels and the risk of different types of strokes. Primordial follicles in fresh and cryopreserved human ovarian cortical grafts can initiate growth after transplantation to immunodeficient mice. Intervention of a biologic agent in some of these oxidative processes is suggested. An Arabidopsis thaliana ABC transporter that confers kanamycin resistance in transgenic plants does not endow resistance to Escherichia coli. Lung cancer mortality risk among breast cancer patients treated with anti-estrogens. This technique may have the potential for the supportive care of patients dying from hypoxia in the setting of reversible lung injury.

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Prostaglandin E (EP) receptor is positively related with COX-2, which is involved in cancer biology. Acknowledgment of the complementary nature of hemodynamic and electrophysiological measures, as reported here in a cognitive task using evoked response analysis in MEG and BOLD signal analysis in fMRI, represents an essential step toward an informed use of multimodal imaging that reaches beyond mere combination of location and timing of neural activation. The influence of nystagmoid oscillation on contrast sensitivity in normal observers. Although the differential diagnosis between renal oncocytoma and hypernephroma may not be possible, preoperative awareness of a potentially benign lesion may guide the surgeon to attempt renal preserving surgery instead of the customary nephrectomy. Development and optimization of cytokine ELISAs using commercial antibody pairs. However, can urethroplasty of the membranous urethra be carried out in these patients without inevitable incontinence?. One of the main reasons of poor adherence to these treatments is the occurrence of adverse events, mainly at gastrointestinal (GI) level, including dyspepsia, dysphagia, and esophageal ulcers. HIF-1 expression is associated with tumorigenesis and angiogenesis. Effect of saturated and unsaturated fatty acids on dietary lipogranuloma.

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Being a recently introduced surgical photorefractive technique for ametropias correction, epipolis laser in-situ keratomileusis is a fast evolving area of interest for refractive surgeons. Primary carcinoma of the fallopian tube is rare, but still occurs frequently enough to warrant consideration when certain specific symptoms are present. The enzymatic conversion of N5-formyl tetrahydrofolic acid (folinic acid) to N10-formyl tetrahydrofolic acid. To determine whether a reactive FTA-ABS after the age of 12 months is indicative of congenital syphilis. Hematological malignancies--a special field of blood system pathology. Instead of a merely phenomenological approach to flow dynamics, pioneers assigned a value of paradigms to basic flow patterns. Improvements in hardware and software and increased reader experience will add value to the local Australian prostate imaging programme. The history of the electrical activity of the brain as a method for localizing sensory function. Our results show that the iridium complex displays a very strong dependence on the electrolyte properties such that large enhancements in catalytic activity may be obtained by adequately choosing pH and anions in the electrolyte. Significance of anomalies and variants of the extrahepatic bile ducts and the pancreatic ducts for therapeutic interventions on the papilla.

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Problems of clinical and gastroscopical characteristics of neurosis with gastric symptom complex. We have devised large scale arrays to measure the antibody response to myelin proteins and lipids. Identification and validation of a novel microRNA-like molecule derived from a cytoplasmic RNA virus antigenome by bioinformatics and experimental approaches. The clinical electro-oculogram (EOG) results were recorded according to the ISCEV standard. Letter: Uneventful delivery of patient with antibody in Knops group. The participation of malonyl coenzyme A in the biosynthesis of mevalonic acid. This is done by using a multiscale method to accurately determine the probability density function over many time scales and by determining how the effective kinetic rate constant, the probability of switching states, depends on the effective time scale at which it is measured.

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Comparison of lanatoside A, B, C, D on the heart-lung preparation in cats. Metastatic calcification in experimental overdosage of dihydrotachysterol in rats. Assay of some vitaminic factors, introduced intravenously, on blood plasma alkaline reserve. Cytotoxicity related to oxidative and nitrosative stress by nitric oxide. Traditionally, a lyophilized cake for reconstitution followed by s.c. Although HPV genotyping is currently not widely available, it may provide important prognostic information. Comparison of techniques improving the resolution of standard Coulter cell sizing systems. Primary or metastatic neoplasms were diagnosed in five men and five women patients ages 38 to 79 years. There is a growing literature regarding the use of recombinant activated factor VII (rFVIIa) (NovoSeven, NovoNordisk, Copenhagen, Denmark) to control refractory hemorrhage after cardiopulmonary bypass in cardiac surgery.

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Cloning of two isoforms of soluble acid invertase of Japanese pear and their expression during fruit development. Endothelium-dependent relaxations are augmented in rats chronically treated with the angiotensin-converting enzyme inhibitor enalapril. This was studied by enzyme-linked immunosorbent assays and by the peptide patterns obtained when 125I-labelled proteoglycans were digested with trypsin. Previously we isolated the Cs-ACS1 (ACS, 1-aminocyclopropane-1-carboxylate synthase) gene that encodes the rate-limiting enzyme in the ethylene biosynthetic pathway. Surgery that preserves the duodenopancreatic region has become well-established in chronic pancreatitis (CP) and some groups have begun to use these techniques to treat benign tumors and even those with uncertain potential malignancy. The influence of training status on oxidative stress in young male handball players. Atractyloside as an inhibitor of phosphorylation coupled with oxidation of succinate in plant mitochondria. Children with a high JL could be drawn toward gymnastics because of their ability to adapt to the constraints of this sport. Ochratoxin A activates opposing c-MET/PI3K/Akt and MAPK/ERK 1-2 pathways in human proximal tubule HK-2 cells. Posttransplantation normoglycemic diabetic nephropathy: the role of the allograft insulin resistance--a case report.

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The disease gene causing Mal de Meleda was first localized at 8q chromosome, and mutations in the ARS (component B) gene encoding SLURP-1 (secreted mammalian Ly-6/uPAR-related protein 1) protein were identified subsequently. Testosterone transport in brain: primary role of plasma protein-bound hormone. Of the 20 patients who were not pretreated, six showed a marked rise of serum myoglobin within 5 minutes, increasing to 150-200 micrograms/litre at 20 minutes. Implications typical max dose of xanax daily of some recent developments in hematological and serological genetics. The identification of I-A(b) restricted AQP4 specific T cell epitopes will allow us to investigate how AQP4 specific autoimmune reactions are regulated and to establish faithful mouse models of NMO that include both cellular and humoral responses against AQP4. Basic Research at State Stations: Twenty-two percent of federal-grant payments to state agricultural experiment stations support basic science.

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There have been numerous replicated empirical findings leading to a significant advance in the understanding of persecutory delusions, now beginning to be translated into cognitive treatments. As distinguished from known gravitational bar detectors it uses the optical interferometrical readout for registering weak variations of gravity gradient at the kilohetz frequency region. Even very weak but positive patterns can be recognized and used for diagnosis. Outcomes of Merkel cell carcinoma treated with radiotherapy without radical surgical excision. Calculation by computer of dose distributions for superficial gold-198 implants and the derivation of optimized distribution rules. The data reported here are part of a wider study that developed and tested a condition-specific, online parent information and support application with children and young people with chronic-kidney disease, parents and professionals. Our experiences with steroid anesthetics in 213 cesarean sections. Here, we describe mutations that abolish regulation by both receptors. Using video capture to investigate the causes of falls in long-term care. Supplemental instruction classes have been shown in many studies to enhance performance in the supported plavix medication group courses and even to improve graduation rates.

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For example, neurofilament protein can move in its particulate or polymeric state, while tubulin can move in its soluble or unpolymerized state. Further testing is required over a range of toxicants and concentration gradients to establish threshold responses and the full compliment of behaviours that could be useful in online biomonitoring. Family support and acceptance, gay male identity formation, and psychological adjustment: a path model. Evaluation of the PAH and water-extractable phenols content in used cross ties from the French rail network. We analyze the clinical outcome after cardiac surgery with a cardioplegic solution based on intracellular components added with histidine-ketoglutarate-tryptophan. The registered electropherograms were pretreated (normalized and aligned) and subjected to multivariate analysis (principal component analysis). In recent years, next generation sequencing (NGS) technologies have appeared and given new perspectives in oncology. H ferritin knockout mice: a model of hyperferritinemia in the absence of iron overload.

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