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Agoxin (Digoxin)

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Agoxin works by blocking the an enzyme in your heart that causes the heart to pump harder with each beat, which helps people with heart failure get more blood and oxygen. Agoxin also slows down the electrical activity in the heart, which helps people who have abnormally fast heart rates due to atrial fibrillation.

Other names for this medication:
Agoxin, Cardiacin, Cardiogoxin, Digacin, Digibind, Digitek, Digobal, Digohan, Digoregen, Digosin, Digossina, Digoxen, Digoxin, Digoxine, Digoxinum, Eudigox, Fargoxin, Halfdigoxin, Lanadicor, Lanibos, Lanicor, Lenoxin, Purgoxin, Sigmaxin, Vidaxil

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Also known as: Digoxin


Agoxin (digoxin) is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.

Agoxin is used to treat heart failure.

Agoxin is also used to treat atrial fibrillation, a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart).


Usual Adult Dose of Agoxin for Congestive Heart Failure:

Rapid Digitalization with a Loading Dose: Peak digoxin body stores of 8 to 12 mcg/kg generally provide a therapeutic effect with minimum risk of toxicity in most patients with heart failure and normal sinus rhythm. The loading dose should be administered in several fractions, with approximately half the total given as the first dose. Additional fractions of the total dose may be given at 6 to 8 hour intervals. Careful assessment of the patient's clinical response should be considered before each additional dose. If the patient's response necessitates a change from the calculated loading dose of digoxin, then calculation of the maintenance dose should be based upon the amount actually given. Tablets: Initial: 500 to 750 mcg usually produces a detectable effect in 0.5 to 2 hours with a maximal effect in 2 to 6 hours. Additional doses of 125 to 375 mcg may be given at 6 to 8 hour intervals until clinical evidence of an adequate effect is noted. The usual amount of digoxin tablets that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 750 to 1250 mcg. Injection: Initial: 400 to 600 mcg of digoxin intravenously usually produces a detectable effect in 5 to 30 minutes with a maximal effect in 1 to 4 hours. Additional doses of 100 to 300 mcg may be given cautiously at 6 to 8 hour intervals until clinical evidence of an adequate effect is noted. The usual amount of digoxin injection that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 600 to 1000 mcg. The injectable route is frequently used to achieve rapid digitalization, with conversion to digoxin tablets for maintenance therapy. Maintenance Dose: The doses of digoxin tablets used in controlled trials in patients with heart failure have ranged from 125 to 500 mcg once daily. In these studies, the digoxin dose has been generally titrated according to the patient's age, lean body weight, and renal function. Therapy is generally initiated at a dose of 250 mcg once daily in patients under age 70 with good renal function.

Usual Adult Dose for Atrial Fibrillation:

Peak digoxin body stores larger than the 8 to 12 mcg/kg required for most patients with heart failure and normal sinus rhythm have been used for control of ventricular rate in patients with atrial fibrillation. Doses of digoxin used for the treatment of chronic atrial fibrillation should be titrated to the minimum dose that achieves the desired ventricular rate control without causing undesirable side effects.

Detailed Agoxin dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of digoxin can be fatal.

Overdose symptoms may include nausea, vomiting, loss of appetite, and feeling tired.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Agoxin dosage information

Side effects

The most common side effects associated with Agoxin are:

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Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Predilatation of a stenotic ostium of a bronchial artery, followed by embolization in recurrent hemoptysis. Bivariate and multivariate regression assessed physical dating violence correlates. Reverse bobbing is usually observed in patients who are unconscious and who have significant pontine pathology and disruption of the reticular formation. Using quality improvement to enhance research readiness in palliative care. Although this study is limited by follow-up and may represent a group of patients with a more vascularly active disease state due to the low proportion of patients with prior peripheral ablation, benemid 500 mg cost this cohort of infants provides results against which future interventions may be compared. The patient received E6010, a derivative of tissue plasminogen activator by intravenous injection for about 2 minutes. Defining subtypes of PD is needed to better understand underlying mechanisms, predict disease course, and eventually design more efficient personalized management strategies. Thyroid gland scintigraphy for in vivo presentation of the signal transduction cascade and beyond. Additional research is needed to identify and monitor changes in the prevalence of zoonotic pathogens in humans, domestic dogs, and wildlife species of critical subsistence, cultural, and economic importance to Arctic peoples.

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An efficient statistic to detect over- and under-represented words in DNA sequences. Low-dose heparin prophylaxis is no contraindication to spinal or epidural anesthesia. Nurses in acute care and outpatient settings are in an ideal position to detect physical abuse and neglect. The management of patients with chronic pelvic and perineal pain requires preliminary clinical analysis designed to identify trigger points responsible for myofascial pain, pelvic floor muscle tension, and lumbar-pelvic-hip instability. The aims of this study were to assess the effect of LMWOAs on uptake of Cd by tobacco and sunflower under pot experiments, thus comparing the ability of tobacco and sunflower for phytoremediation. Standard diagnostic tests are readily available for BT/EHD viruses, and there are described tests that are published in the World Organization for Animal Health (OIE) Terrestrial Manual.

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Using genetically-defined rodent strains for the identification of hippocampal traits relevant for two-way avoidance behavior: a non-invasive approach. Clinician diagnostic delays of up to 36 months did not correlate with worsening prognostic factors or with survival rates. Development and validation of electronic surveillance tool for acute kidney injury: A retrospective analysis. The 90-day hospital readmission rates for those with ABSSSIs may be reduced when combination therapy is utilized. C-Fos activity was elevated in the medial amygdala ( rocaltrol tab uses MeA) and reduced in the bed nucleus of the stria terminalis (BNST) during novelty exposure, regardless of separation. Using the retrieving effectively from memory (REM) model of recognition memory, we tested a familiarity-based account of the pseudoword effect: Specifically, the pseudoword effect arises because pseudowords lack distinctive semantic meanings. It has been applied to a wide range of experimental models: bacteria, fungi, cells culture, arthropods, fishes, amphibians, reptiles, mammals, and humans. Integrative vectors for constructing single-copy transcriptional fusions between Bacillus subtilis promoters and various reporter genes encoding heat-stable enzymes.

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Sphingosine kinase 1 (SPHK1) is involved in various cellular functions, including cell growth, migration, apoptosis, cytoskeleton architecture and calcium homoeostasis, etc. The prevention of further infection through the counselling and treatment of partners contributes to the sexual health of patients. Macrofocal multiple myeloma in young patients: a distinct entity with favorable prognosis. Genes encoding dihydrofolate reductase, thymidylate synthase, serine hydroxymethyl transferase, a cdc2 kinase-like protein and helicase ERCC6-like protein were each located on a single chromosome whereas genes for both beta-tubulin and aminopeptidase were on two different chromosomes. Lobe-based computed tomography assessment of airway diameter, airway or vessel number, and emphysema extent in relation to the clinical outcomes of COPD. The Michaelis constant (K(m)) and Vmax for several proline-containing dipeptides were determined. Exposure of a wild type cell population to gradually increasing concentrations of DL-alpha-difluoromethylornithine resulted in the selection of a strain of Leishmania, which was capable of proliferating in 5 mM DFMO with an IC50 value of 10 mM.

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However, there are 3 affected males in this kindred, and 2 of the 3 had significant anomalies. 3D printing and numerical analysis are combined to design a new class of architected materials that contain bistable beam elements and exhibit controlled trapping of elastic energy. We hypothesized that the initial heart rate (HR) at presentation and the number of nebulizer treatments would predict visit disposition adequately and that existing triage criteria would not. Predicted distribution data make explicit inferences on species occurrence and their commission and omission errors depend on model structure, on the omission of variables that determine species distribution and on data resolution. Dimer/monomer equilibrium and domain separations of Escherichia coli ribosomal protein L7/L12. In all eyes, ophthalmic examination was performed in the same order as follows: Ocular Surface Disease Index (OSDI) survey, tear film osmolarity measurement with TearLab Osmolarity System, tear meniscus measurements by OCT, corneal fluorescein staining scoring, conjunctival lissamine green staining scoring, tear film breakup time assessment, and anesthetized Schirmer test.

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