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Alfacalcirol (Calcitriol)
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Alfacalcirol

Alfacalcirol is a synthetic physiologically-active analog of vitamin D, specifically the vitamin D3 form. Alfacalcirol regulates calcium in vivo by promoting absorption in the intestine, reabsorption in the kidneys, and, along with parathyroid hormone, regulation of bone growth. Alfacalcirol receptor-binding protein appears to exist in the mucosa of human intestine.

Other names for this medication:
Alcee, Alfabond, Alfacal, Alfacalcirol, Alfacip, Alphadol, Apcical, Arcium, Biocal, Calasto, Calbory, Calcibest, Calcikind, Calcimet, Calcirol, Calotec, Calsure, Caltin, Caltive, Caltop, Carcal, Citroj, Coecoral, Denscal, Devita, Estovon, Fovit, Koncal, Laretol, Novadee, Nutribone, Osteobel, Ostriol, Primacal, Refirm, Riecal, Rockbon, Roical, Trolec, Vitalpha

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Flomax, Prandin, Sustiva, Cozaar, Moduretic, Aricept, Periactin, Azulfidine, Nephral, Lanzol, Randec, Pentakool, Ordipha, Prodroxy, Dulife, Balarm, Silenor, Preglon,

Also known as: Calcitriol

Description

Generic Alfacalcirol is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Alfacalcirol are intestine and bone. Generic Alfacalcirol receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Alfacalcirol may also act on the kidney and the parathyroid glands. Generic Alfacalcirol is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Alfacalcirol has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Alfacalcirol, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Alfacalcirol in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Alfacalcirol produces other independent beneficial effects. Alfacalcirol is also known as Calcitriol. Generic Alfacalcirol treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Alfacalcirol is Calcitriol. Brand name of Generic Alfacalcirol is Alfacalcirol.

Dosage

Generic Alfacalcirol is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Alfacalcirol suddenly.

Overdose

If you overdose Generic Alfacalcirol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Alfacalcirol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

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Humans are accidental/dead end hosts of JEV infection because they cannot sustain high viral titers. Flaps ranged in size from 75 to 648 cm, and all but one were cutaneous in nature with the other one being fasciocutaneous. The new method avoids the need to perform elaborate colloid reactions to prepare the NP building blocks. Furthermore, we demonstrate, that activation of trigeminal nociceptors by peripheral inflammation causes significant increase in expression of IL-1B, IL-6, TNF and BDNF in male mice, comparing to female mice. The patient, a 74-year-old man, consulted our hospital with complaints of back pain and abdominal mass in right flank. Specifically, three comprehensive bipartite networks: EF-miRNA, EF-disease and miRNA-disease associations, were constructed to build predictive models. Assessment of diastolic function and left ventricular filling pressures in the setting of both normal and reduced systolic function is of major importance particularly in patients with dyspnea. The clinical presentation is characterized by rapidly progressive renal failure with oliguria or anuria and in case of lung involvement, pulmonary hemorrhage responsible of hemoptysis, sometimes massive.

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