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Allofex (Fexofenadine)

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Allofex is used for treating seasonal allergy symptoms such as sneezing, runny nose, itchy throat, or itchy, watery eyes, skin itching and hives caused by a condition called chronic idiopathic urticaria.

Other names for this medication:
Afexdine, Allefast, Allofex, Ancofex, Biofen, Exfen, Faydine, Fegix, Fenadin, Fenax, Fenofex, Fexise, Fexodine, Fexodis, Fexody, Fexofast, Fexofen, Fexofenadine, Fexohist, Fexokast, Fexon, Fexoquin, Fexor, Fexoriv, Fexot, Fexotab, Fexotec, Fexotive, Fexova, Fexozide, Fextral, Histaloc, Infexo, Intrafen, Madexa, Maxgra, Montair, Monten, Nexofex, Ofena, Oregra, Radifex, Rafen, Xdine, Zegra

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Also known as: Fexofenadine


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


Use Allofex exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Take the regular tablet with a full glass of water. Do not use any other type of liquid. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

To take fexofenadine orally disintegrating tablets (Allofex ODT):

Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet. Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

Take the Allofex disintegrating tablet on an empty stomach, at least 1 hour before or 2 hours after a meal.

Tell your doctor if your symptoms do not improve, or if they get worse after you start taking Allofex. Never use more than the recommended dose.

Store Allofex at room temperature away from moisture and heat. Keep the medicine bottle tightly closed.

Detailed Allofex dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include dry mouth, dizziness, or drowsiness.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

Side effects

The most common side effects associated with Allofex are:

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The elderly are usually more sensitive to the effects of this medicine, especially if it contains:

Antihistamines—Confusion, difficult or painful urination, dizziness, drowsiness, feeling faint, or dryness of mouth, nose, or throat may be more likely to occur in elderly patients. Also, nightmares or unusual excitement, nervousness, restlessness, or irritability may be more likely to occur in the elderly taking antihistamines. Decongestants (e.g., ephedrine, phenylephrine, pseudoephedrine—Confusion, hallucinations, drowsiness, or convulsions (seizures) may be more likely to occur in the elderly, who are usually more sensitive to the effects of this medicine. Also, increases in blood pressure may be more likely to occur in elderly persons taking decongestants.

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A simple radioimmunoassay of plasma testosterone without column chromatography. Bringing prostate cancer quality of life research back to the bedside: translating numbers into a format that patients can understand. A computational investigation on the role of glycosylation in the binding of alpha1 nicotinic acetylcholine receptor with two alpha-neurotoxins. Calmodulin-mediated cell cycle regulation: new mechanisms for old observations. In breast tissue, the luminal epithelial cells express CK 8/18, CK 7 and CK 19, while basal/myoepithelial cells express CK 5/6, CK 14 and CK 17.

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These marks were examined and compared with the teeth of a suspect arsonist. The study established widespread nutritional deficiencies with low-income household cohorts bearing a greater burden of the deficiencies. Butadiene and mixtures of butadiene and styrene were genotoxic in mice, as shown by a significant increase in the frequency of micronucleated polychromatic erythrocytes. Ultrastructure of sensory cells in the pineal body of Phoxinus laevis L. The therapeutic detoxification of chlorogenic acid against acetaminophen-induced liver injury by ameliorating hepatic inflammation. However, the mean value of serum ferritin differed significantly among the three groups, with the lowest values found in newborns of mothers with iron deficiency anaemia. Chronic obstructive pulmonary disease (COPD) is characterised by insidiously progressive airflow limitation. Cutaneous basophil hypersensitivity in contact-sensitized guinea pigs.

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The in vitro color stability of acrylic resins for provisional restorations. Long-term streptozotocin-induced diabetes alters prostanoid production in rat aorta and mesenteric bed. The interference of pharmaceuticals with endogenous and xenobiotic metabolizing enzymes in carp liver: an in-vitro study. Cataract develops earlier in life in populations with low income and inferior education. Germination of food grains improved the bioaccessibility of iron but not that of zinc. Together with similar previous findings in the unstimulated allergic nasal mucosa these results suggest that glucocorticosteroids induce a decrease in the mast cell histamine pool, possibly due to an inhibition of the intracellular synthesis of histamine.

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Microscopic analysis of prostate glands from individual males (three lines) showed that these glands were often abnormal, with increased accumulation of cells in the prostatic stroma as well as the epithelium. Nurses in the sample reported significantly greater problems than the norm in dealing with stress (as measured by the nurse stress index). Staining could be localized far more precisely in these sections than in paraffin sections owing to the thickness of the semithin sections and to the excellent structural preservation of cellular components. Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models. The diagnosis of learning disabilities: a neurologic screening test to identify children at high risk. These results demonstrate the presence of striking functional differences between the cysteine-rich regions of nPKCdelta and the calcium-dependent isoform, cPKCgamma, where both cysteine-rich regions represent functional PDBu binding elements. Assessments were performed before and after the program using the Subjective Units of Distress for mind and body and the Two-Dimensional Mood Scale. We demonstrated in a recent Plant Journal article that the receptor-like protein CLV2 and the receptor-kinases BAM1 and BAM2 also bind to the CLV3 CLE peptide ligand with an affinity similar to that of CLV1. The five most common ARCA in this cohort were Friedreich ataxia, ataxia with isolated vitamin E deficiency, ataxia with oculomotor apraxia type 2, autosomal recessive spastic ataxia of Charlevoix-Saguenay and ataxia with oculomotor apraxia type 1. Microvasculopathy is one of the characteristic features in patients with systemic sclerosis (SSc), but underlying mechanisms still remain uncertain.

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Secondary hyperparathyroidism and hypovitaminosis D in African-Americans with decompensated heart failure. The third stage in clinical training (the 2d half of the 2d year). The purpose of this prospective clinical study was to assess and quantify the association between the presence of a palmaris longus tendon and carpal tunnel syndrome. Anatomical comparisons and quantitative analyses of the two circuits reveal a high inter-individual stereotypy of the cell complement, neuronal projections, and synaptic connectivity, including the left-right asymmetry in the connectivity of some neurons. It was shown that the yeast growth was inhibited by lovastatin in concentrations of 0.25 to 5.0 micrograms/ml when the inhibitor was added to the cultivation medium either with the inoculum or at later periods of the yeast cultivation. The methods that are best used to satisfy these requirements are less clear and more open to interpretation by both sponsors and Agency reviewers. Evidence for nitrite reductase activity in intact mouse Leydig tumor cells. Inducible VC in wild-type animals is also an important research tool for developing preventive and therapeutic approach for VC.

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On the use of some plastic substances (dacron, teflon) in surgery of retinal detachment. Audit of the influence of body mass index on the performance of epidural analgesia in labour and the subsequent mode of delivery. Phosphoserine phosphatase deficiency in a patient with Williams syndrome. Triplet repeat primed PCR (TP PCR) gives a characteristic ladder on the fluorescence trace enabling the rapid identification of large pathogenetic CAG repeats that cannot be amplified using flanking primers. Over the last two decades the rise in the prevalence rates of overweight and obesity likely explains the NAFLD epidemic worldwide. The simulations predicted that without a voluntary drive (rest tremor) the neural drives would be more likely in phase, while a concurrent voluntary input (postural tremor) would lead more frequently to an out-of-phase pattern.

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Development and Application of a High-Resolution Imaging Mass Spectrometer for the Study of Plant Tissues. Culicoides biting midges serve as vectors of pathogens affecting humans and domestic animals. They are financed through the general account in Japan, while in Korea a foundation for health promotion has been established and the income from tobacco tax is ring-fenced for this fund. Analysis of mice lacking IRS-1 confirms an important physiological role for this protein in glucose metabolism and general cell growth in the intact animal. The patients did not show any dysfunction of the phonological loop, reflected by the presence of phonological similarity and word length effects, but had lower spans than controls. We compared species density of vascular plants, birds, bees, grasshoppers and crickets, and spiders on 202 paired fields, one with an agri-environment scheme, the other conventionally managed. Association of psychic stress with clinical severity and symptoms of psoriatic patients. To study the relation between the interval from diagnosis to initiation of intravitreal injection therapy and visual outcome in neovascular age-related macular degeneration (nAMD) and to report changes over time in fellow-eye status. None of the two dentin-bonding agents could prevent the formation of a contraction gap of any of the four resins, but the results obtained with the anterior material were significantly better than those obtained with the posterior resins. Theophylline, in both children and adults, and enprophylline (not yet studied in children) may modify both the early and late responses, but do not appear to have an effect on bronchial hyperreactivity.

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In pithed rats intravenous administration of serotonin (5.0, 10.0, 20.0, 30.0 and 50.0 micrograms/kg) produced a dose-dependent increase in blood pressure. Interstitial pneumonitis, especially associated with cytomegalovirus (CMV) infection, is a serious complication after bone marrow transplantation (BMT), with a high fatality rate despite adequate antiviral treatment. This would suggest that local mechanisms are operational and may influence renal blood flow in the human fetus with intrauterine growth retardation. Cancellation of motion artifact in MRI due to 2D rigid translational motion. Medical safety and side effects of methadone in tolerant individuals. Visible signs of disease presence included 1 or more rust-colored leading edges, with or without a trailing area of necrotic tissue, such that the lesion forms a contiguous band around part or all of the sponge branch. B-tropic Friend virus: a host-range pseudotype of spleen focus-forming virus (SFFV). A chart review of all idiopathic clubfoot at a single institution treated by either the Ponseti method or short leg casting and surgery were reviewed for adalat 30 mg recurrent deformity involving the tibia, ankle, or foot.

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The published data on results, prognostic factors, and technical aspects of treatment with combined irradiation and operation are examined, as well as those pertaining to treatment with irradiation alone. Many clinical preventive care services are recommended for adolescents. A force was then applied to the medial calcaneal tuberosity until failure occurred. In the present study, the sensitivities of the developing rat CNS to hypoxic/ischemic neuronal degeneration and to the neurotoxic action of NMA were compared at various postnatal ages. This allows us to make some testable hypothesis on the nature of the interaction between distant portions of the DNA chain which led to the DNA structure that we observe today in higher eukaryotes. Total ankle replacement in association with hindfoot fusion: Outcome and complications. Doses to patients in interventional radiology are generally higher than for other fluoroscopically guided procedures. Cartilage content of proteoglycans decreases early in induced degenerative hip joint disease. The more differentiated tissues were usually circumscribed by fibrocellular bands of spindle-shaped cells that seemed to have transformed into rounded cartilaginous cells. These Bcl-2-expressing monocytes spontaneously undergo macrophage differentiation.

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American Academy of Pediatrics Committee on Sports Medicine and Fitness. Markers of inflammation, the profiles of serum (apo)(lipo) proteins as well as classical risk factors were determined in 270 clinically stable zofran medication 4mg angiographically documented subjects. Unlike the dramatically accelerated age-linked decline of thymulin production reported in females of other autoimmune strains (measured as early as 6 weeks of age), only male BXSB were affected, as compared to normal strains. Bone remodelling is controlled by systemic hormones and cytokines and is an integral part of the calcium homeostatic system. Optimization criteria of the mechanism governing the stability of the membrane potential. GLUT 1 mRNA quantity decreased whereas GLUT 2 increased with age. This approach and the fidelity of the biochemical properties of the beta2AR/S65T/GFP demonstrate that real-time optical measurements of beta2AR (as well as other GPCR) interactions and dynamics on living cells are feasible. Gas exchange variables, end tidal CO(2) (P(ET)CO(2)) and the ratio of ventilation to CO(2) production (V(E)/VCO(2)), during submaximal exercise were able to track patient responses to therapy over a 3-5 month period.

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The role of brain acetylcholine in GABAA receptor antagonist-induced blood-pressure changes in rat. Both systems showed strong induction of tetracycline-responsive promoters upon administration of the appropriate ligands (doxycycline and dexamethasone for TetA-GBD, and doxycycline and tebufenozide for TetA-EcR), and undetectable leakiness when compared with classical TetActivators. Ligands for the vitamin D receptor (VDR) regulate apolipoprotein A-I (apo A-I) gene expression in a tissue-specific manner. Attentional measures were assessed with a visual discrimination paradigm. The study supports the recommendation of a once-daily morning dosage regimen of pantoprazole 40 mg in the treatment of acid-related diseases.

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The findings suggest that a classification system in which subsets of the disease that are defined according to a combination of cross-sectional criteria and the disease progression may be useful in studies of EOP. Methods of roentgenological studies of what drug class does plavix belong to patients during the acute period of cerebro-cranial injuries. Effects of discontinuing coffee intake on iron status of iron-deficient Guatemalan toddlers: a randomized intervention study. Hemagglutinating activity of Escherichia coli isolated from the respiratory tract in comparison with those isolated from urine feces and blood. Does coexistence of ochronosis and ankylosing spondylitis really exist?.

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Unilateral pedicle screw fixation versus its combination with contralateral translaminar facet screw fixation for the treatment of single segmental lower lumbar vertebra diseases. The purpose of this study was to assess the precision at the implant interface of titanium, zirconia, and alumina Procera abutments with a hexagonal connection for single-tooth restorations. Hypochlorous acid and its pharmacological antagonism: an update picture. Adrenergic innervation of the parasympathetic ciliary ganglion in the chick. During night, all components decreased in parallel with plasma albumin. The kallikrein excretion was statistically adjusted to account for variations in body size and urine output. Juvenile bladder stones are typically urate and oxalate in small boys in certain stone belts. It is recommended that the upper limit for protein content of infant formulas be decreased from 4.5 g/100 kcal to 3.2 g/100 kcal and that an upper limit for phosphorus concentration of infant formulas be set at 93 mg/100 kcal. Molecular epidemiology of Mycobacterium abscessus complex isolates in Ireland. Mailed survey of 3394 life-science faculty in the 50 universities that received the most funding from the National Institutes of Health in 1993.

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In order to compare the safety and the antiemetic effectiveness of tetracosactide (TCS) or beta 1,24 ACTH with those of dexamethasone (DXM) as an adjunct to high-dose metoclopramide, diphenhydramine and clorazepate, 33 patients receiving cisplatin based cancer chemotherapy were enrolled in a double-blind cross-over clinical trial. The comparison data further highlight the need for continued norvasc 10 mg bid targeted effort to improve safe sleep behaviors to improve infant health outcomes. The genus Microbotryum includes plant pathogenic fungi afflicting a wide variety of hosts with anther smut disease. Mucosal leishmaniasis is uncommon outside Central and South America, where it is commonly caused by Leishmania (L.) braziliensis. However, immunoprecipitation assay revealed that p40-phox was dissociated from p47-phox and p67-phox during activation. These effectomes accommodate a broad range of protein functions like enzymes related to glycolysis/gluconeogenesis and the TCA cycle, ATP synthases, aminoacyl-tRNA synthetases, chaperones, proteases that degrade misfolded proteins, protectants against oxidative damage, as well as cold shock and outer membrane proteins.

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Computed tomographic scan and magnetic resonance imaging showed a 44 x 20 mm solid tumor in the right adrenal region. Human subjects first learned to categorize stimuli within limited training regions, and then, during fMRI scanning, they also categorized transfer stimuli from new regions of perceptual space. Peanut agglutinin (PNA) was the only lectin used that showed a differentiation stage-dependent binding to oligodendrocytes. Human cDNA homologous to p97 was cloned, and its nucleotide sequence demonstrates that the 840-base pair repetitive sequence and one of the intramolecular repeats are missing. The parasite, Dirofilaria repens, was in all the cases a female. Effects of zinc deficiency on morphogenesis of the fetal rat eye. The patients were randomized into two groups, one of which received perioperative antibiotics for twenty-four hours (twenty-four-hour group) and the other of which received antibiotics for the duration that the drain was in place (drain-duration group). This paper summarizes the first conclusions arising from an analysis of parasite diversity in blood samples collected during longitudinal surveys conducted in Senegal. Although the antimicrobial therapy recommended in outpatients older than 60 years or with 1 comorbidity or more is more costly, this observational study provides no evidence of improved medical outcomes in the small subgroup who received ATS guideline-recommended therapy. Menkes disease and Wilson disease are human disorders of copper transport caused by mutations in distinct genes encoding similar copper-transporting P-type ATPases.

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To evaluate the role of fibronectin in staphylococcal adhesion to explanted plates and screws, a mutant of S. Noncompetitive binding tests showed that the ST-7 antiserum had specific affinity for the rat free alpha-subunit, but not for rat intact LH, FSH, and TSH. In 3 cases complications during conventional appendicectomy were treated laparoscopically. In an integrated multidisciplinary approach to dental care, it is logical that periodontal treatment precede final restorative procedures. cleocin gel 1% PropBank and NomBank from newswire and BioProp from biomedical literature were used as source domain datasets. Patients who underwent sacrospinous ligament suspension between 1978 and 1991 were evaluated from follow-up visits, telephone interviews, questionnaires, and chart reviews. The relative merits of ET-converting enzyme inhibitors and receptor antagonists for the treatment of cardiovascular disease are discussed. Biological variation as a result of population-specific tolerance, if not addressed, can be misinterpreted as experimental error.

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