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Alprasan (Alprazolam)

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Alprasan is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprasan, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprasan is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alcicalm, Allam, Almac, Alpra, Alpraquil, Alprocalm, Alprogard, Alpron, Alzopax, Alzoset, Ambusyn, Anxigon, Belfa, Betapax, Deproz, Dizeral, Emlol, Fledore, Fludep, Fluti, Fluwel, Mebasap, Niravam, Nokzok, Omelam, Pacyl, Paxor, Pizolam, Prazil, Rivcam, Rozin, Samrox, Selamb, Setex, Setlan, Synozolam, Tenil, Tranisol, Trapose, Unixl, Xylonite, Zamitol, Zolax, Zolorest

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Also known as: Alprazolam


Alprasan is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alprasan is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alprasan if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alprasan or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alprasan. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


Take Alprasan XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Alprasan XR may be habit-forming and should be used only by the person it was prescribed for. Alprasan XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Alprasan extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Alprasan XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Alprasan XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Alprasan XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Alprasan XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Alprasan XR dosage information


If you have been prescribed Alprasan for medical reasons, the best way to avoid a Alprasan overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprasan consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprasan dosage information

Side effects

The most common side effects associated with Alprasan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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About a simple method to prevent accidents caused by changes in positioning in surgery: The transparent head drape. Pancreatic tissue from normal dogs and tumor tissue from three dogs with histologically-confirmed insulinomas was examined for expression of KATP channel subunits (SUR1 and Kir6.2) using RT-PCR. Design and methods of a strategic outcome study for chronic kidney disease: Frontier of Renal Outcome Modifications in Japan. Children aged 2-36 months with peripheral blood culture results from February 2004 to June 2008. Comparative analyses identify USH and its human homolog, FOG2, as the targets of fly miR-8 and human miR-200, respectively. The intensity of erythema and oedema induced by a 48-hr human patch test was consistent with the amount of IL-1alpha secreted in the medium, the histological appearance of the Reconstituted Epidermis and the cell viability. Moreover, derangements of several pathways induced by Hcy are demonstrated with adverse effects on both reproduction and long term health. Psychogeriatric and geriatric medicine in Germany after reunification. Augmentation of corrosive gastric stricture by a segment of transverse colon is an innovative, practical, and useful procedure, although long-term results are awaited. Recently, combinations of UV filters with agents active in DNA repair have been introduced in order to improve photoprotection.

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Note: Continuing improvements on the novel flat-response x-ray detector. Such advantages, however, may become disadvantages if appropriate cares are not taken. Postoperative follow up for 6 months to 8 years and 4 months showed satisfactory results with good appearance and function. Histological examination identified a spreading melanoma reaching the lower dermis (Clark level IV). Combination of Pd, supported on alkaline earth type supports with a lipase results in a selective catalytic system for dynamic kinetic resolution of benzylic amines. Emergency physicians demonstrate outcome bias in cases of intermediate quality more than in cases in which the quality of care is clear. In spite of its agricultural importance, the genomics and genetics of the pathogen are poorly characterized. Towards optimal alignment of protein structure distance matrices. Consecutive asthma patients presenting to the asthma clinic underwent a brief, structured psychiatric interview, completed the Asthma Control Questionnaire (ACQ) and Asthma Quality of Life Questionnaire (AQLQ), and reported the frequency of bronchodilator use in the past week.

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Further research might be of value for a better understanding of the pathophysiological basis of the clinical heterogeneity in this disease. Color flow Doppler imaging was used to obtain fetal renal artery flow velocity waveforms in 130 normal fetuses at various gestational ages to build a database for the establishment of normal ranges for the Pulsatility Index in the fetal renal arteries throughout pregnancy. More interestingly, a longer RT in the no-vision/touch than in the vision and no-vision conditions was observed. Lesions of GLv caused no deficits in pattern discrimination performance. At 1:100 dilution, however, only development of the Wolffian duct was prevented, as indicated by the absence of regions of the Wolffian duct or by the presence of epithelial disintegration throughout the ductal lumen. In particular, Ku70 S155A/D156A affected the IR-induced transcriptional response of several activating transcription factor 2 (ATF2)-regulated genes involved in apoptosis regulation. rTMS (condition A) involved the delivery of 10 trains of 100 stimuli at 20 Hz using a stimulator with a 70-mm figure-of-eight coil to elicit a contraction of the abductor pollicis brevis. Thus, SQSTM1/p62 gene mutations may confer an increased lifetime risk of developing PDB. Patients who benefit the most from the program are patients who have a low degree of self-reflectiveness and patients who are concomitantly preoccupied by their symptoms.

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Nickel-Catalyzed Cycloisomerization of Enynes: Catalyst Generation via C-H Activation of Carbene Ligands. A synergistic increase in potency of a multimerized VP16 transcriptional activation domain. Inducement of a heat-shock requirement for germination and production of increased heat resistance in Bacillus fastidiosus spores by manganous ions. This study was designed to evaluate the accuracy of high-resolution ultrasonography in measuring radial artery IMT in pre-dialysis uraemic patients. Our data revealed that 100 ng of IL-12/mouse/day used in combination with FR-WBH was as effective as one in which 300 ng of IL-12/mouse/day was used alone. Acute rejection occurred in all of the untreated recipients of allogeneic orthotopic liver transplants, and all died within 30 days. The physicochemical properties and endothelial cell compatibility of the chitosan films were investigated. The present study was designed to determine whether patients with adenomatous polyps of the colon, which have a tendency to develop synchronous malignancies of the colon, have any disturbance in mucosal cell proliferation. The results obtained are similar to the findings in a number of animal species and may represent the morphological basis for a counter-current exchange mechanism.

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Household obligations may have important implications for cardiovascular health, meriting further empirical attention. This was associated with induction of IL-18 and reduction of IL-18BP expression, while IL-18R expression remained stable. Mechanisms that contribute to the spatial distribution of transcription factors within the three dimensional context of nuclear architecture control the sorting and integration of regulatory information as well as the combinatorial assembly, organization and activities of transcriptional machinery at scaffold-associated subnuclear sites that support gene expression. Augmentation therapy in alpha-1 antitrypsin deficiency: advances and controversies. Heparin allergy: successful desensitization for cardiopulmonary bypass.

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The resulting method can be used in assays for a particular target or for purification and concentration of analytes prior to further examination by another technique. Greater net triiodothyronine formation results if greater amounts of exogenous thyroxine are added to the system, with no plateau evident even at very high thyroxine concentrations. Phosphorylation can affect protein localization, protein interactions, and protein function. The molluscicidal activity of Sapindus mukorossi and Terminalia chebula fruit powder against the vector snail Lymnaea acuminata was time and concentration dependent. In a previous study, an ibuprofen/paracetamol combination provided significantly better analgesic efficacy than comparable doses of ibuprofen or paracetamol alone in patients experiencing moderate to severe acute postoperative pain after extraction of impacted third molars.

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Is conservative management of prenatal and neonatal ovarian cysts justifiable?. Clinical assessment of serial computerized tomography scanning in severe head injury. Standard application procedures of IOLs may alter the IOL surface. For one thing, it will have only a single kind of entry (Concept), rather than three (Concept, Related, and Synonym). 60 adult, ASA physical status I, II, and III patients presenting for total knee arthroplasty. Trial of labor following cesarean section: a two-year experience. Change in clinical management of sentinel lymph node location in early stage cervical cancer: the role of SPECT/CT. It is a partnership between the Health Promotion Service (HPS), the three education sectors, parent groups, other health services and The Cancer Council NSW. Compared to dialysis patients, sickle cell disease patients scored similarly on physical role and emotional role function, social functioning and mental health, worse on bodily pain, general health and vitality and better on physical functioning. Prevention of streptococcic lymphadenitis in swine: effectiveness of selected antibiotics and a modified live-GES vaccine.

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Differences in molecular charge or shape are probably responsible for the slightly reduced filtration of IFN-beta. This may explain earlier contradictory findings on the ability of B. When administered 30 min after the onset of behavioral epileptic seizures, transient attenuation of ictal behavior was observed in animals treated with 800 mg/kg or more of LEV. Topiramate reduces the frequency, but not severity or duration, of perimenstrual migraines in women with MRM, including migraines with and without aura, and regardless of combined oral contraceptive use. Residues at the indole-NH of LE300 modulate affinities and selectivities for dopamine receptors. Studies of the early stages of schizophrenia suggest that thalamic volume reduction is present early in the course of the illness. This paper aims to investigate the usability of this method by assessing three different morphologic characteristics in a sample of South African blacks: shape of the greater sciatic notch, mandibular ramus flexure, and shape of the orbits. Herb-drug interactions also occur at the level of the P450 hepatic enzyme system of drug catabolism and the P-glycoprotein transport system regulating the entry of exogenous compounds into the vasculature or blood-brain barrier. NIM combined with DDP shows significantly synergistic anti-tumor effects on lung cancer cell line A549 and subcutaneous implanted tumor on nude mice, which may be achieved by enhancement of growth inhibition and apoptosis induction to tumor cells. Serum creatinine remained above pre-treatment values in seven patients.

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This suggests that DNA crosslink lesions may play a rle in sunburn cell production. MA showed lower values of wall thickness, LV dimensions and LV mass compared with HYP and HCM. Conventional linear criteria with sample entropy in the interpretation of reactive antepartum fetal heart rate tracings. Our purpose was to evaluate the presence of inflammation in the colonic mucosa of patients with symptomatic uncomplicated diverticular disease compared with subjects without diverticula. Distribution of NMDAR1 and subunits (alpha1 and alpha3) of GABAA receptor in the cerebellar cortex of adult rhesus macaques. Multi-unit recordings with tetrodes have been used in brain studies for many years, but surprisingly, scarcely in the cerebellum. Only one fifth of them also showed movement-related activity with stimulus-triggered movements, including trigger responses. This is in accordance with the findings of the Diabetes Control and Complications Trial (DCCT).

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Action of hypothyroidism on the metabolic maturation of the pyramidal neurons of the rat hippocampus. A survey on attitudes and behaviours towards preventive measures against pandemic H1N1 influenza 2009 was carried out during the month of October 2009 in Italy through an online questionnaire adapted to the Italian situation from a similar survey of the Harvard School of Public Health in the United States (US). Hematopoiesis of human yolk sac and the culture of yolk sac endothelial cells. Anatomy and computed tomography of the limbs: horizontal cross-sections every 9 mm. We sought to determine whether the epithelial to mesenchymal transition (EMT) is impaired in MSI-positive CRCs that characteristically have a mutant transforming growth factor-beta receptor type II (TGFBR2) gene. Minimally invasive approaches to rectal cancer need to demonstrate equivalent oncologic outcomes and maintenance or improvement in quality of life.

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The rabbits were killed two weeks (fourteen rabbits) or five weeks (fourteen rabbits) after the operative procedures. The application of HERMES to this case study shows that the methodology is applicable in practice and can give valuable and significant results. We observed multiple flat wart-like lesions on the chest, neck and extremities of an adult T-cell leukemia patient. Altogether, our results suggest that restoring EBP50 expression could suppress breast cancer cell proliferation by promoting cell apoptosis and inhibiting ERK activity, and that EBP50 may be a target for development of diagnostics and therapeutics in breast cancer. Dynamics of free amino acid reserves in newborn 3, 6, 12 and 24-month rats was studied in ontogenesis. Transformation of filamentous fungi based on hygromycin B and phleomycin resistance markers albenza drug class . A technique for salvage of the infected diabetic gangrenous foot.

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Superfluidity, the ability of a fluid to move without dissipation, is one of the most spectacular manifestations of the quantum nature of matter. This is considered the main cause for the age-related deterioration of various immune functions and, ultimately, for the increased incidence of infectious, neoplastic, and automimmune diseases in old age. A single-subject multiple baseline design across subjects with probes was utilized with ten subjects with chronic stroke disability. These results demonstrate high concordance between coding and non-coding regions of mtDNA, and provide further evidence that the eastern wolf possessed distinct mtDNA lineages prior to recent coyote introgression. This dynamic coupling between chemistry and processing requires the extensive use and development of complementary ex situ measurements with in situ characterization techniques, following in real time the molecular precursor solutions to the formation of the final hybrid organic-inorganic membranes. The results provide rich mechanistic information regarding molecular aberrations and gene expressions in cancer genomes.

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Scanning electron microscope-energy-dispersive X-ray analyses showed that, in the absence of cells, a Ca-P layer formed on the material surface because of the dissolution-precipitation reaction. Here, this balance between energy and entropy or particle size is traced through the theory of simple fluids, begining with Andrews and van der Waals, the subsequent developments of perturbation theory, theories of correlation functions that are based on the Ornstein-Zernike relation and the mean spherical approximation, electrolytes, and recent work on ion channels in biological membranes, where the competition between energy and size gives an intuitively attractive explanation of the selectivity of cation channels. Isolation and characterization of the fertility factor P of Vibrio cholerae. It is a methodology that can suggest corrective or preventive action for future practice and thereby minimize the risk of future errors. They support the usefulness of otoacoustic emissions in early detection of cochlear dysfunction. Evaluation of the stability of methylcobalamine in gastric and intestinal juice. Examination of the electrostatic potential of a modeled complex, consisting of the Klenow fragment of E. In addition, a human cross-over study was performed, measuring the plasma status of carotenoids in humans consuming diets made from crops from these agricultural systems.

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Mechanisms of thermogenic responses that play a role to maintain homeothermy during an early stage of neonatal chicks on acute cold exposure are scarcely studied as hatchlings are believed to be poikilothermic. The laboratory tests showed mild leucopenia and mild thrombocytopenia that gradually returned to normal within 2 months. Confirmation of the role of pneumolysin in ocular infections with Streptococcus pneumoniae. The activity of BCKA dehydrogenase was increased by the addition of the cytoplasmic fraction of the gastro-cnemius muscle to liver mitochondria. This kit does not use aggressive organic solvents and RNA free of genomic protonix tabs DNA was isolated without the need for DNase treatment. Endothelial survival in cryopreserved human corneas: a scanning electron microscopic study. Inhibition of spinal dorsal horn neuronal responses to noxious skin heating by medial hypothalamic stimulation in the cat. Factors that promote tumorigenesis encompass a wide array of proteins that include transcription factors, signal transduction molecules, negative regulators of tumor suppressors, transmembrane receptors and enzymes involved in a variety of processes. The vastus lateralis muscle flap in head and neck reconstruction: an alternative flap for soft tissue defects. Effect of prenatal androgen treatment on maternal behavior in the female rat.

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When crossed with another transgenic mice expressing Cre under the Podocin promoter (a podocyte specific gene bromocriptine dosage formulations ), the intervening lacZ gene was removed activating the expression of Nef in podocytes. Features shared by bipedal and quadrupedal locomotion that were quite different from human locomotion were also observed: the heel never contacted the ground, a foot longitudinal arch was absent, the hallux was widely abducted, and the functional axis was on the third digit, not the second. Biosafety when working with human tissue, which is often pathogenic, is important. The TRITON versus PLATO trials: differences beyond platelet inhibition. Both hearing children and deaf children made significantly more mistakes on pseudohomophones than on control pseudo-words.

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This study assesses pre-existing comorbidities, adjusted risks of postoperative major morbidities and mortality in intellectually disabled surgical patients. It is hypothesized that the maintenance of olfactory bulb responses to conditioned odors during training may allow for activation of long-term memory mechanisms. They immediately examined their behaviors during the time they wore the CGM. Spatial distribution of the Sm antigen in Drosophila early embryos. torques could explain increased total mucosa-associated bacteria in IBD. Children with hearing impairment have balance and motor deficits primarily due to concomitant damage to the vestibular structures. lividus forms during metamorphosis as a composite of apical epidermal tissue that grows inward and ventral foregut tissue that extends outward.

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Collaborations among the Athletic Training Education Program, the Department of Dance, and the University Central Administration. Together, these data suggest that YDJ1p functions in polypeptide translocation in a conserved manner, probably acting at organelle membranes and in association with hsp70 proteins. Host factors interfering with results of clinical tests: analysis of factors and their elimination-viewpoint of the clinical laboratory. However, an undesirable but often accepted increase in posterior tibial slope and decrease in patellar height are still routinely seen. Surgical correction of rare variant of cor triatriatum with absent coronary sinus. The revascularisation of muscle has been the important step forward but the re-focusing of interest norvasc drug classification in this condition has brought about a number of peripheral advances. Indirect effects in community ecology: Their definition, study and importance.

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At intervals, they were challenged with 200 to 230 cercariae per mouse and 500 to 520 cercariae per rat. The Na,K-adenosine triphosphatase (ATPase), or sodium pump, has been well studied for its role in the regulation of ion homeostasis in mammalian cells. We compared the fit of two types of models to lung-function measurements: models based on the covariates used in standard prediction equations and models incorporating ancestry. This collective behavior is a suitable way to perform a large range of tasks and positional assembly manipulation in a complex three-dimensional workspace. The observed patterns may reflect socio-demographic or geographic variations in risk factors or access to cancer services. The fate of this tissue is variable and cannot be predicted based on the ADC alone. Computational models have a long history in contributing to the understanding of cardiac physiology and are useful for identifying biological mechanisms, inferring multiscale consequences to cell signaling activities and reducing the complexity of large data sets. DBA/1J mice were injected with several combinations of mAbs followed by lipopolysaccharide. Clinical spectrum and management of ovarian tumours norfloxacin and tinidazole dose in young girls up to 20 years of age. It is acceptable practice to excise aggressive variants of this lesion during pregnancy to avoid distressing side effects.

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If LFTs were persistently raised and/or the CBD was dilated on ultrasound, patients underwent pre-operative ERCP. Our objective was to review a specific surgical treatment plan for forefoot deformities classified by us as Type 2 arch collapse and evaluate the outcomes. SLEDAI-2K 30 days scores were concordant with SLEDAI-2K 10 days scores, both in patients in remission and in patients with a spectrum of disease activity levels followed monthly over 1 year. 6,7-Dihydroxytetrahydroisoquinoline: electron microscopic evidence for uptake into the amine-binding vesicles in sympathetic nerves of rat iris and pineal gland. Here, we examine fOSGN2-P generation in cells from patients with type I Congenital Disorders of Glycosylation (CDG I) in which defects in the dolichol cycle cause accumulation of immature DLO intermediates and protein hypoglycosylation. Decreased endothelial permeability in the iridocorneal endothelial syndrome. Objective diagnosis of pulmonary vessels and heart configuration from native thoracic radiography in healthy infants and small children and in children with congenital heart defects. Embryonic male germ cells exposed in utero to the class I/II histone deacetylase (HDAC) inhibitor, trichostatin-A (TSA), show premature Stra8 activation and meiotic entry without altered Cyp26b1 expression. Diagnoses included traumatic brain injury (15 zantac 75 mg dosage patients), anoxia (one patient), and spinal cord injury (one patient). It is a potent hypotensive agent and one of the most potent stimulators of cardiac contractility.

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