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Alprazan (Alprazolam)

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Alprazan is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprazan, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprazan is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alfix, Alpaz, Alpose, Alprogard, Alpron, Alrif, Alzot, Ambulax, Ambutech, Andep, Anzilum, Anzocalm, Benzax, Depsolam, Dizeral, Elzopam, Emlol, Flunix, Imprax, Mcalm, Mebrin, Mediprex, Omelam, Pifzot, Plaxid, Proprazolam, Sertamax, Setlan, Tenan, Tenil, Trapose, Trazopin, Viprax, Zocam

Similar Products:
Aldactone, Cymbalta, Nolvadex, Floxin, Paxil, Rocaltrol, Maxalt, Copax, Sugafen, Zedd, Bisoaps, Flavozan, Controlip, Perindan, Ramimed, Bioprim,

Also known as: Alprazolam


Alprazan XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alprazan XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alprazan XR may also be used for other purposes not listed in this medication guide.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alprazan dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprazan XR dosage information

Side effects

The most common side effects associated with Alprazan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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By using a DNase I footprinting assay, we have purified a factor by DNA affinity chromatography that binds to the minimal enhancer region of the Drosophila knirps gene and subsequently identified the protein as the core histone H2B. Uridine-5-diphosphoglucose in the therapy of hepatopathies of diverse etiology. We study the penetrable sphere (alias square mound) model in the fluid phase by means of the virial expansion, molecular dynamics simulations, and Ornstein-Zernike integral equation. The proposed method realizes better performance than other heuristic methods on various model and real networks. Combined fractional diagonal chromatography (COFRADIC) was used to isolate protein N-terminal peptides from three different proteome preparations, and following LC-MS/MS analysis, over 621 different proteins were identified by their N-terminal peptides. For increasing particle densities, a crossover takes place from a two-particle interaction into a collective many-body interaction, where the dipole-dipole or van der Waals blockade phenomenon between the Rydberg levels plays a dominant role.

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Herbivore-induced plant volatiles trigger sporulation in entomopathogenic fungi: the case of Neozygites tanajoae infecting the cassava green mite. Loss of enzymatic activity yielded a much smaller mass indicating a robust structure in which catalytic activity could be expressed in cleaved polypeptides. Identification of myosin heavy chain I, IIa and IIx in canine skeletal muscles by an electrophoretic and immunoblotting study. Absolute perfusion values were assessed for 18 myocardial segments without any normalization and using the three different normalization methods. Alcohol intoxication and occasional smoking: a field investigation. Second, it was investigated whether the number of intermediate pitches created with DES can be predicted from SOE, channel interaction measures, current distribution in the cochlea, or distance of the electrode to the medial wall. In clb5Delta cells, centromere cluster resolution appears normal, whereas dissolution of the vegetative telomere clusters is impaired and meiosis-specific clustering of telomeres, i.e.

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Mg is necessary for normal growth, however the mechanism is unclear. Consensus approach is only an interim guide to a complex disorder such as HAE and should be replaced as soon as possible with large phase III and IV clinical trials, meta analyses, and using data base registry validation of approaches including quality of life and cost benefit analyses, followed by large head-to-head clinical trials and then evidence-based guidelines and standards for HAE disease management. In addition, no significant treatment effects were observed when corn, feces and urine samples were evaluated for the presence of mutagenic substances. Sleep EEG power spectra characteristics in healthy infants evolve in keeping with maturation and neurodevelopmental milestones. Thus, we tested whether selective 5-HT(2A) receptor antagonist, M100907, might abolish phencyclidine (PCP)-induced attentional performance deficit by preventing its effects on transduction mechanisms leading to CREB phosphorylation. Vi serology in screening of typhoid carriers: improved specificity by detection of Vi antibodies by counterimmunoelectrophoresis. The histiocytes contain a few to many intracellular yeast-form cells that resemble cellular debris because of their small size and staining pattern. The structure of glisoprenins A and B, novel acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors, was determined by spectroscopic analyses, mainly 1H and 13C NMR and MS. DES was not different from SES in terms of channel interaction and SOE. Relative expression of pknI, when measured by combining molecular beacons and RT-PCR, decreased during infection of THP-1 human macrophages.

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Seasonal occurrence of trombiculid mites species and Leptotrombidium kawamurai (Acarina, Trombiculidae) as a carrier of Rickettsia orientalis in the Nopporo area, Hokkaido, Japan. Dermoscopy is an in vivo, noninvasive technique that improves the clinical accuracy in diagnosing melanoma and other pigmented skin lesions. LG1506 elevates high-density lipoprotein cholesterol in humanized apolipoprotein A-1-transgenic mice. Allergic rhinitis is a core component in the specialty of otolaryngology head and neck surgery. These patients had taken corticosteroids for a long time for RA control. C-band heterochromatin polymorphism of human chromosomes 1, 9, 16, Y. Recommendations for the next decade of research and some implications of family-based treatment for child and adolescent psychiatry are explored.

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As new therapies are being considered, the time of administration is becoming a central point of study for the application of novel therapeutic initiatives. To characterize factors associated to diagnostic crossover from anorexia nervosa restricting type (ANR) and anorexia nervosa binge-purging type (ANBP) to bulimia nervosa (BN) and to compare BN individuals with initial ANR or ANBP to subjects with stable BN. Infants and other vulnerable groups were most likely to sleep under the most protective nets. The applicability of the approach was demonstrated for a sediment extract and a dust extract. We analytically show that their usage indeed increases the critical connectivity. First a fuzzy classifier was generated with a set of 216 primary lung cancer patients (158 non-small cell lung cancer (NSCLC) and 58 small cell lung cancer (SCLC) patients) and 127 patients suffering from pneumoconiosis (51 silicosis and 76 asbestosis). Inter-observer agreement in clinical decision-making for abnormal cardiotocogram during labour: a comparison between CTG and CTG plus STAN.

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IgE containing cells in the nasal mucosa of the patients with nasal allergy. The effects of several factors (age, SE, axial length, gender and eye) on RNFLT were investigated in univariate and multivariate stepwise regression analyses. We recommend that the baseline genitourinary function should be evaluated before the treatment for male rectal cancer patients, and penile rehabilitation is necessary for their quality of life after treatment. Identification of immunodominant Th1-type T cell epitopes from Schistosoma japonicum 28 kDa glutathione-S-transferase, a vaccine candidate. We have incorporated the enediyne group into 10- (4-10) and 12-membered ring (11) cyclic amino acids and dipeptides, respectively, and explored their relative reactivity toward cyclization, varying N-substitution in the case of the 10-membered ring substrate, which gave the expected cyclization products in good yields when using either thermal conditions in the presence or absence of microwave irradiation. Beta-phenylethylamine stimulates striatal acetylcholine release through activation of the AMPA glutamatergic pathway. Erythema dyschromicum perstans (EDP) is a cutaneous pigmentary disturbance originally considered to be a variant of erythema perstans.

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Ten patients with generalized aggressive periodontitis, 10 patients with chronic periodontitis, and 10 healthy controls were included in this study. The results of this comparison show that the most common target gene for real-time PCR assays is the IS1111 repeat element that is present in multiple copies in the C. Systematic reviews (SRs) of clinical trials strive to organize the entire body of evidence while minimizing bias so that policy makers and guideline developers can base their recommendations on the appropriate strength and level of evidence. These receptor cells are associated with ovipositor muscle fibers and were preferentially responsive to muscle tension and not muscle length. In addition, we present evidence that the sustained self-renewal in Zap70KD is associated with enhanced Jak/Stat3 signaling and c-Myc induction. Since the primary site for active bile acid reabsorption is via ASBT, which is localized on the luminal surface of the distal ileum, we reasoned that a nonsystemic inhibitor would be desirable to minimize or eliminate potential systemic side effects of an absorbed drug. Ultrasound microbubble-mediated siMDR1s delivery effectively inhibited MDR1 expression at both mRNA and protein levels and decreased P-glycoprotein function. Sensitivity of erythrocyte sedimentation rate and C-reactive protein for the exclusion of septic arthritis in emergency department patients. Protective effect of diversion of the urinary stream on dog bladder.

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Recent studies have provided new insights into the mechanism by which the site of contractile ring norvasc overdose treatment assembly is specified. Validation results on linearity, specificity, accuracy, precision as well as application to the analysis of samples taken up to 120 h after oral administration of 20 mg of paroxetine in 28 healthy volunteers were found to be of good performance in bioequivalence study. Targeting T cells with bispecific antibodies for cancer therapy. However, SNP and sodium nitrite induced significant methemoglobin formation from HBOC, whereas nitroglycerin did not. Expression of c-fos and AP-1 activity in senescent human fibroblasts is not sufficient for DNA synthesis. The effect of glycine-conjugated bile acids on net water and glucose transport, and transmural potential difference, across isolated rat jejunum. Findings are consistent with previous studies indicating that many mental health consumers spend considerable amounts of time involved in sleep and passive leisure. These results suggested that hyperhomo-cysteinemia increased the incidence of thrombotic disease, which may be caused by decreasing the activity of fibrinolytic system, whereas, folic acid may be protective against the toxic action of Hcy. Use of gel retardation to analyze protein-nucleic acid interactions. Evaluation of the solubility and emulsifying property of soybean proglycinin and rapeseed procruciferin in relation to structure modified by protein engineering.

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These ultra-small nanocrystals exhibit broadband emission (420-710 nm) that covers most of the visible spectrum while not suffering from self absorption. Influencing of the thrombocytopathy due to uremia by hemo- and peritoneal dialysis. Pharmacists, given the proper training, can be effective at offering preventive pharmaceutical care for decreasing high blood cholesterol and the risk for coronary heart disease through patient counseling on TLC components as well as drug therapy in patients with dyslipidemias. Multiple endovascular interventions exist for the treatment of lower extremity peripheral arterial disease (PAD), with some exhibiting better outcomes than others. A portable chest radiograph demonstrated bilateral alveolar infiltration suggesting pulmonary edema. The induction of HSP70 and HSP23 was markedly reduced or absent in mutant embryos harboring a deletion of the menin gene. Why do we need a national joint replacement registry in the United States?. The measured expansion closely approximated the expansion expected by incorporation of the molecules. TGF-beta1 (10 and 100 ng/ml) stimulated both (3)H-proline and (35)S-sulfate uptake, showing a dose-dependent response for both and a temporal response for (35)S-sulfate uptake.

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In clinical evaluation, we consider the cerebellum as a kind of computer to get information from the peripheral structures and also higher motor cortical centers including the primary motor cortex (M1) and send a cerebellar command to M1 after computation of much information. Tooth sensitivity was assessed at pre- and postcementation time points using categorical and visual analogue scale (VAS) assessment measures. Genes for Panton Valentine leukocidin, which are present in the majority of community-associated MRSA, are thought to enhance the ability of S aureus to cause necrotizing pneumonia. A patient with recurrent coarctation of the aorta was treated by a bypass between ascending and descending aorta performed through a right-sided thoracotomy. Thus, SGECs express three B7-2 alternate transcripts that encode the full-length protein, the soluble form and a truncated membrane-bound molecule, that lacks the IgV-like counter-receptor binding domain and has a negative regulatory role. We report three cases of scrub typhus presenting with confirmed MAS between January 2007 and December 2007 to a tertiary care hospital in South India.

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This autocrine mechanism might contribute to glomerulosclerosis in renal diseases such as diabetic nephropathy. Fourteen male predominantly medicated schizophrenics and matched non-ill controls were administered the WCST and tests of temporal lobe (delayed verbal and spatial memory) and general intellectual functioning (Shipley). Inhibition of adenosine metabolism increases myocardial interstitial adenosine concentrations and coronary flow. A genetic approach to identifying the functions of metalloproteinases and their inhibitors in adult and developing mice. The damage effect of the combined irradiation of 1omega and 3omega in multilayer films was investigated.

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Measures of effectiveness included the number of additional diagnostic procedures, time to last diagnostic procedure, and number of days absent from work. The study of congenic strains on a BALB/c background has shown that background genes, as well as the H-2 associated Ped gene, play a role in the control of the rate of early embryonic cleavage. Digital recordings of the psychometrically equivalent word recognition lists are available on compact disc. Data from eight patients who had undergone 34 sessions of SBRT was analyzed. The split between these two lineages was estimated to occur in the Middle Pleistocene, when populations were isolated in disjunct wetlands with little or no gene flow. Recently it has been demonstrated that short term hyperoxic ventilation (HV) can improve glucose metabolism, reduce pulmonary and hepatic apoptosis, and improve gastrointestinal perfusion during acute sepsis. Sequence of psychotherapy in a hospitalized anorectic patient, illustrating a point in its evolution. However, their main drawback is that they are computationally expensive to implement, and require amiloride hcl dosage large numbers of parameters.

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The purpose of this study was to assess the factors associated with EBF in Nigeria. There are many reports of enhanced transcription and replication in different cell culture systems exposed to electromagnetic fields, and reports of cytoreduction (necrosis and apoptosis) in tumors transplanted into animals exposed to similar, often much stronger electromagnetic fields, but where heating is negligible. ALOX5AP haplotypes that associate with CVD are not associated with obesity or insulin resistance. Incentive-elicited mesolimbic activation and externalizing symptomatology in adolescents. In addition, we compared the actions of agomelatine to those of melatonin and S32006, a selective antagonist at 5-HT(2C) receptors. Ceruloplasmin deficiency results in an anxiety phenotype involving deficits in hippocampal iron, serotonin, and BDNF. Immune dysfunction and post-injury infections are complications associated with thermal injury. Data were obtained from a prospectively maintained foregut surgery database and via follow-up survey. Correlations between oncogenic and chemical properties of several derivatives of 3-hydroxyxanthine and 3-hydroxyguanine.

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The nucleation rates have been estimated for precipitation with and without ultrasound and hydroxypropyl methyl cellulose (HPMC). A fast, standardized method to investigate gastrointestinal lymph nodes. Magnetic resonance imaging revealed a left-sided T1-T2 herniated disc compressing the T1 nerve root. The model was extended to simulate treatment decisions and effects. The study consisted of a cohort of 131 consecutive patients with PCNSV who were seen at the Mayo Clinic over a 25-year period from 1983 to 2007. It is an example of an innovative approach to meeting the social male yeast infection treatment diflucan and recreational needs of individuals with dementia.

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Individuals with fibromyalgia and depression: findings from a nationally representative Canadian survey. Therefore, it is of some value to the epidemiological study, prevention and early detection of cardiovascular disease. In animal-pollinated plants, both the spatial distribution of flowering individuals and the number of flowers that an individual displays affect pollen deposition rates and female reproductive success. Each adipokine gene expressed in dog white adipocytes was also expressed in the differentiated cells. EPR of vanadyl impurity in zinc ammonium trihydrogen bis(orthophosphate) monohydrate single crystal. A sphingosine 1-phosphate receptor, S1P(1), was internalized much faster by the treatment of S1P(1)-overexpressing cells with conditioned medium of ceramidase transfectants than that of mock transfectants. We also examined caveolin-1 levels and other aging markers, such as p53 and p21, in the corneal epithelium.

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Fungal sensitization is more closely associated with AD than RAD. Experimental studies on compensatory hypertrophy of kidney in rabbits. Indirect assay of beta hydroxy beta methyl glutaryl CoA reductase in the sera of leprosy patients--a further probe into cholesterol metabolism. These discussion forums have not yet been the object of much scientific research. Group differences and comparison of pre/posttest scores to evaluate what class of drug is ceftin efficacy of lecture styles were performed with the Student t test. Serotonin transporter activity and serotonin concentration in platelets of patients with irritable bowel syndrome: effect of gender.

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All compounds were tested both in the absence and in the presence of fetal calf serum in the culture medium. MRI changes have been included in the new classification criteria of early axial SPA and are now considered as a major tool in the diagnosis. The mechanism of the association between blood transfusion and cancer mortality warrants further research. Health-related, self-report (HRSR) scale and the diagnostic screening test for depression in a Thai population were used for evaluation. Reduced representation methods for subgenomic enrichment and next-generation sequencing. Fundoplication anastomosis during esophagectomy is effective in protecting patients from reflux symptoms after esophagectomy and improves quality of life, particularly with regard to sleep disturbance. We describe a rare case of multiple arteriovenous fistulae of the spinal cord (SCAVF) in the same myelomer in a five-year-old boy.

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Large scale analysis of virulence genes in Escherichia coli strains isolated from Avalon Bay, CA. A review of the ASPCA Animal Poison Control Center database revealed 347 cases of PAP exposure in dogs during 2000-2009 underscoring the importance of being aware of this toxicity in the dog. Outcome variable was a 6-month depressive and/or anxiety diagnosis after 2 years of follow-up. As with all forms of meta-analysis, the results are based on the assumption that the studies and intervention groupings are sufficiently similar to be compared. To illustrate this we present MRI, biopsy and autopsy specimens from bevacizumab-treated patients.Moreover, while treatment of other tumour types may be improved by combining chemotherapy with anti-angiogenic drugs, inhibiting angiogenesis in GBM may antagonise the efficacy of chemotherapeutic drugs by normalising the blood-brain barrier function. The Jak2/Stat5 pathway is the principal route by which PRL/GH activate target genes. Diversity of cholesterol exchange explained by dissolution into water. Studies of the brain have progressed will biaxin help bladder infection enormously through the use of in vivo and in vitro non-human models. Thus, it is considered that n-3 PUFAs will protect against atopic sensitization and against the clinical manifestations of atopy. Systemic thrombolytic therapy in acute ischemic stroke--new experiences in spreading network of stroke units in Croatia.

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In order to overcome these drawbacks, this study presents an Extended Kalman Filter for fusion of inertial and magnetic sensing that is used to estimate relative positions and orientations. Gastrointestinal stromal tumours (GIST) first described in 1983 are the commonest mesenchymal neoplsams of the digestive tract. Infection preventionist checklist to improve culture and reduce central line-associated bloodstream infections. Execution of an apoptotic program includes energy-dependent steps, including kinase signaling, formation of the apoptosome, and effector caspase activation. Based on these findings, we propose a cyclical model in which 1) apoA-I mass moves from pre-beta HDL to alpha HDL in connection with the action of LCAT and the generation of cholesteryl esters within the HDL, and 2) apoA-I moves from alpha HDL to pre-beta HDL in connection with the action of CETP and the movement of cholesteryl esters out of the HDL. The experiments on both synthetically generated data and real 3-D medical images demonstrate that the proposed approach has superior performance compared to some well-known methods. Transforming ethnocentricity in nursing: a culturally relevant experience of reciprocal visits between Malta and the Midwest. These results have important implications for the impact of juvenile stress on adult neuronal plasticity and on the understanding the functions of the different sectors of the hippocampus. Comparative study of the responses of bovine and mouse intestinal mucosa to iron-dependent lipid peroxidation.

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