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Alprazolam is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alprazolam is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alprazolam may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Actirax, Alpkair, Alprastan, Alprocalm, Alpronit, Altin, Alzopax, Alzorix, Ambusyn, Anlzium, Anxigon, Anxorel, Azicalm, Depsolam, Depten, Destres, Dexolam, Faxtin, Fluwel, Himzolam, Luzarn, Nokzok, Optizole, Ozolam, Pecalm, Pralam, Pranol, Resta, Resto, Riolam, Samrox, Sanprazole, Sertakem, Setex, Tancalm, Tenil, Texidep, Xanti, Zedel, Zeecam, Zopain

Similar Products:
Claritin, Glyburide, Lioresal, Minipress, Lexapro, Zocor, Ilosone, Mircette, Ciprofloksacin, Tacstead, Zacet, Dytide, Veega, Albenzole,


Alprazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alprazolam is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alprazolam if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alprazolam or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alprazolam. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprazolam XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprazolam dosage information

Side effects

The most common side effects associated with Alprazolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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Liquid-chromatographic determination of nicotine and cotinine in urine from test-persons of environmental surveys. Heparin, a potent blood anticoagulant, has been shown to exert a variety of pharmacological activities. Macrostructure in the narratives of Estonian children with typical development and language impairment. It has also been demonstrated that, in secondary oocytes from mice receiving vincristine, the number of both multivesicular bodies and vesicles falling to one vesicular complex profile was higher than in the control group. Quantities of venom (total protein content) and its proteolytic activity from snakes of different ages were compared. BirA enzyme with bioactivity is prepared successfully, which can be used for studying the interaction between protein and protein.

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In early/severe/diffuse ARDS prone position reduces lower inflection point pressure and increases upper inflection point UIP volume of the lung PV curve. However, the mechanisms of targeting are unknown and recent data have highlighted the role of regulating mutagenic repair to limit the accumulation of somatic mutations resulting from the more widely distributed AID-induced lesions to the Ig genes. Using bulk population sequencing and a sensitive limiting dilution analysis, the selection of K65R or other resistance mutations did not occur in HIV, suggesting that adefovir can be confidently used as hepatitis B virus (HBV) therapy in HIV/HBV-co-infected patients who do not require antiretroviral therapy. We extend all approximations to multideme metapopulations with arbitrary population structure. Development of a computational method to automatically acquire ED crowding data. National surveillance capacity of water-related diseases in the WHO European region.

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Effects of konjac glucomannan on putative risk factors for colon carcinogenesis in rats fed a high-fat diet. Development of a model of information security requirements for enterprise-wide medical information systems. The patient was discharged from the emergency room after receiving subcutaneous terbutaline and intravenous aminophylline. There is still controversy as to whether the presence of anti-PF4/heparin antibodies in hemodialysis patients augments clot formation in access fistula thrombosis, peripheral artery disease (PAD), and coronary heart disease (CHD). This review summarizes the pharmacology, clinical trial results, and future role of the new oral anticoagulants in clinical practice. Patients with opioid pharmacotherapy for chronic pain who undergo surgery merit special attention for acute pain management. Flow cytometry was used to analyze the proportion of Th17 cells in jejunum. In cooperatively breeding birds, individuals that appear capable of reproducing on their own may instead assist others with their breeding efforts.

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Fifth European Workshop on Periodontology: Etiology and Pathogenesis Leading to Preventive Concepts. Degradation of myofibrillar proteins, myofibril examination and determination of free calcium levels. Sexual maturation, evaluating from GSI and the spermatogenetic stages, proceeded earlier in the fish population at Toyama Bay, and afterward it was followed in the fish population at the Takahara River, in associated with a rise of environmental water temperature at fish captured sites. Interaction between organophosphate compounds and cholinergic functions during development. Qualitative studies were examined to reveal the subjective experiences of stroke and stroke recovery, paying particular attention to the development of needs across time and context. We used analysis of non-stationary noise to estimate the maximal probability the nicotinic alpha4beta2 receptor is open. There was no significant difference for MDA levels between each other in the groups 1, 2, and 3. Resistance of Staphylococcus aureus mediated by the penicillinase (Pc-ase) plasmid to divalent metal ions of Hg and Cd was found to be controlled by different mechanisms.

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Rapid communications: antiperspirant induced DNA damage in canine cells by comet assay. Cardio-pulmonary function during ether-air-relaxant anaesthesia. Experiments on learning lists of terms and using them as part of a gene tagger on a corpus of abstracts from the scientific literature show that our automatically generated term lists significantly boost the precision of a state-of-the-art CRF-based gene tagger to a degree that is competitive with using hand curated lists and boosts recall to a degree that surpasses that of the hand-curated lists. Furthermore, the temporal difference in the expression of the two genes indicates that the relative contribution of the two pannexins in immature and mature neuronal circuits may vary. Alkyl derivatives of 3-substituted propylamines (with IC50 values of 0.4 mM), on the other hand, were unable to release acrolein after the oxidative deamination, which was further confirmed by a lack of liberation of acrolein from the authentic 3-butoxypropanal. Accidental hypothermia treated with rapid rewarming by immersion. How to halve the prematurity rates of in vitro fertilization pregnancies in 4 days. Using Texas as a case study, we demonstrate that market power can greatly effect the emissions benefits of wind, due to most of the coal-fired generation being owned by the two dominant firms. Methadone-naloxone mixtures for use in methadone maintenance programs.

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Studies of hypothalamic control of somatotropin incretion in acromegaly. Emetine-induced lactate dehydrogenase release, functional changes and electrocardiographic changes in the rat heart in vitro. CTGF was tested in ovarian organ cultures and found to stimulate primordial follicle development. Apoptotic cell death was also observed during early development of zebrafish when CUG2 was overexpressed in zebrafish embryo. Little is known about the effects of mobile teledermatology services on diagnostic accuracy and their appropriateness for skin tumour surveillance. An autopsy case of spontaneous rupture of aortic arch through an atheromatous plaque which resulted in pseudoaneurysm is reported.

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In particular, rates of emergency presentations for intoxication and alcohol-related ambulance attendances increased dramatically. Transmigration of permanent mandibular canines is a very rare phenomenon and has no definite etiology. Besides, inhibition of Ras-dependent signaling pathway may be involved in these processes. Effect of human placenta derived mesenchymal stem cells on cord blood lymphocyte transformation. A novel patient-specific navigational template for cervical pedicle screw placement.

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Effect of grass or concentrate feeding systems on lamb carcass and meat quality. Addition of sodium hydrogen sulphite and other nucleophilic agents to pteridin-4-one and related compounds. Semi-automatic determination of tissue lipoprotein lipase in man and animals. Asthma leads to structural changes in the airways, including the modification of extracellular matrix proteins such as tenascin-C. Correlation of pancreatic blood flow and high-energy phosphates during experimental pancreatitis. A method for preparation of thylakoids from plant leaves on a large scale is described. Computed tomography scan showed a right cerebellar and subarachnoid hemorrhage.

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This study evaluates the roles of genetic variations of hepatitis B virus (HBV) and aflatoxin B(1) (AFB(1)) exposure in the formation of HCC in this high-risk area. Vector systems based on inversion of the gene trap module have recently been devised to allow for conditional mutagenesis. These data should not lead to the rejection of protease inhibitors but should strengthen the prevention of cardiovascular diseases as an integral part of the management of HIV patients. The purpose of this study was to understand the relationship between daily contextual factors and oral contraceptive (OC) adherence among students who attend college or graduate school. While dental caries is an infectious transmissible disease with children being at the highest risk, primary prevention can reduce this risk. Lifespan complex cognitive activity may therefore protect against dementia through multiple biological pathways. A magnetic resonance cholangiopancreatography was carried out according to our diagnostic work-up of patients with unexplained pancreatic hyperenzymemia. There is a lack of information about the prevalence of stress and types of stressors experienced by Emergency Department (ED) patients. To study the transcutaneous absorption of traditionally massaged oil in newborns and to specifically compare the effects of (i) essential fatty acid (EFA) rich - safflower oil and (ii) saturated fat rich coconut oil, on fatty acid profiles of massaged babies. We review and discuss two efficient parametrization schemes for the electronic wave function, the matrix product states and the complete-graph tensor network states.

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We conducted a nested case-control study of 88 patients experiencing CA on the wards of a university hospital between November 2008 and January 2011, matched 1:4 to 352 control subjects residing on the same ward at the same time as the case CA. Osteoclasts play a key role in the pathogenesis of bone erosion and systemic bone mass loss during rheumatoid arthritis (RA). Is it not time for instituting an independent department for intensive care in type I hospitals?. Screening for breast cancer in ambulatory gynecological practice. Evaluations were performed before treatment, on the first, second and third month of treatment and one month after treatment. Control animals exhibited very little or no c-Fos in the above areas. Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis.

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Acuity was approximately constant over a wide range of modulation periods from 50 to 150 msec when expressed in terms of phase angle, but fell off rapidly at higher and at lower frequencies. The purpose of this paper is to demonstrate that such discrepancies exist and to confirm specimens with accurate ages, which can be marked for future research. The attainment of automated handwriting was markedly slower in children with handwriting deficits and DCD, who used a faster stroke velocity to write simple characters (1.22 times those without handwriting deficits), but when writing complex characters, their stroke velocity and pen force were lower (0.85 and 0.89 times those without handwriting deficits, respectively). After standard laparoscopic dissection and vascular control, the colon is divided distally, whereas the proximal colonic end is ligated to prevent fecal spillage. The association and discrimination of diesel samples was largely unaffected by temperature programs that incorporated one- or two-step temperature ramps. Neither the antimineralocorticoid RU 28318 nor the maximum dose of amaryl per day antiglucocorticoid RU 38486 alone had any effect on forskolin-stimulated CRF release. Kinetics, surface structures, and extent of surface coverage in adsorption of spherical colloids onto uniform and charge-patterned surfaces are studied using dynamic simulations. Although statistically significant differences were observed for oral symptoms, emotional well-being and social well-being, with the first administration of the interviewer-administered version, the effect of the order of administration had small to medium effects on the CPQ scores.

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The putative ligand-binding domain (LBD) of the receptor directly bound PGA2, and LBD-deleted receptor showed little transcriptional activation by PGA2. Lipid and fatty acid composition of rabbit meat: Part 1.-Apolar fraction. The XSV genome (linear ss-RNA), 796 nucleotides long, contains a single ORF coding for the XSV coat protein CP-17. Treatment with the cytokine G-CSF improved HSPC survival after exposure to oxidative stress and rescued the transplantation defect in Nrf2(-/-) cells despite increases in ROS induced by cytokine signaling. Flumecinol was extracted from plasma with diethyl ether and analysed by gas-liquid chromatography using a flame ionisation detector (FID). For that reason there is a need for further diagnostic criteria. We reviewed our experiences with ureterorenoscopy and Holmium laser lithotripsy (UL) for the primary management of large and complex intrarenal calculi. Partial wedge resection of the anterior uterine wall via abdominal myomectomy and total abdominal hysterectomy.

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Current antivirals, including peg-interferons, are limited by substantial toxicities that compromise their efficacy. pH, meat colour, protein extractability and pigment content, measured on Swedish pig carcasses, were analysed by principal component analysis (PCA). Possibilities of prevention of this complication - which are cited in literature - are mentioned. Snellen decimal best-corrected visual acuity, fulfilment of driving standards, and eligibility for partial sight and blind registration at the last clinic visit. Identification of molecular-mimicry-based ligands for cholera diagnostics using magnetic relaxation. The results demonstrate an impairment of the GH-IGFs system in ALS. Among the different testicular cell types, Sertoli and Leydig cells, have been the ones most usually used for the in vitro analysis of toxic compounds. The results suggest that this approach will be useful for separating changes in the kinetics of serotonin uptake by endothelial cells from effects of changes in flow and perfusion heterogeneity. A study was designed to test this hypothesis and to control for the effect of affective disorders on catecholamine metabolism. A mean number of 5.5 perforators with a mean diameter of 0.9 mm (range, 0.5 to 1.5 mm) supplied this zone.

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CDD reconstruction was used in patients who received a liver transplant for a diagnosis of PSC, congenital hepatic fibrosis, biliary atresia, and Alagille syndrome. Finally, we will attempt to critically assess and explain the shortcomings of LTL as a biomarker and identify further research avenues that require further investigation before telomere length can be implemented as an individual biomarker for cardiovascular aging. Intestinal loads of lysine and histidine and their concentration in systemic blood plasma of pigs after feeding. Photophysical properties and photodynamic activity of octacationic oxotitanium(IV) phthalocyanines. A fasciotomy of her right calf was does klonopin help alcohol withdrawal done for compartment syndrome. A 30-item multiple-choice questionnaire was administered to 435 hematologists and oncohematologists in 16 Latin American countries. Namely, the retention of some tissue-specific stem cell attributes, like the ability to asymmetrically self-renew, impacts the natural history of human tumor development. Current experience allows the following conclusions: The chemotaxis test in microtiter plates is simpler, faster and uses less material than conventional Boyden chambers.

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Surgery for aneurysms in a symptomfree state, while rupture is still absent, is of definite benefit to the survival rate. A higher understanding of genetic and genomic bases of partial resistance in plants and their diversity regarding pathogen variability is required for a more durable management of resistance genetic factors in sustainable cropping systems. Individual bands were excised, in-gel trypsinized and subjected to LC/ESI-MS/MS. National park development in China: conservation or commercialization?. Possibility of using the determination of minimal residual disease in pancreatic adenocarcinoma using real-time RT-PCR--a pilot study. The goal of this article is to provide a modern outcomes-oriented approach to the question of limb salvage versus amputation.

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The experimental observations are in agreement with a quantum mechanical strong-field model. A transgenic papaya line (TPY10-4) that is resistant to both papaya ringspot virus (PRSV) and papaya leaf distortion mosaic virus (PLDMV) has been developed in Taiwan. Isotopic decay curves of cholic acid, chenodeoxycholic acid and deoxycholic acid acquired in three recent human studies were analysed. Analysis of LUTS/BPH-related determinants in community-dwelling men in the city of Herne, Germany after exclusion of subgroups with co-morbidities or co-medications with can you drink alcohol if taking lipitor possible influence on the key items. The objective of this study was to compare the expression of Col1a1, Col1a2, and procollagen I in the seminiferous tubules of immature and adult mice and to characterize the cellular expression pattern of procollagen I in germ cells during spermatogenesis in order to provide necessary groundwork for further functional studies in the process of spermatogenesis. In September 2007, Congress passed the Food and Drug Administration Amendments Act of 2007 (FDAAA).

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None of these patients have had loosening, implant failures, dislocations, periprosthetic fractures, or infections. The sensitivity of this assay was evaluated by comparing detection limits of nested PCR and conventional PCR. The major antiinflammatory effects of glucocorticoids appear to be due largely to interaction between the activated glucocorticoid receptor and transcription factors, notably nuclear factor-kappaB (NF-kappaB) and activator protein-1, that mediate the expression of inflammatory genes. Examination for abdominal cavity contamination following Cesarean section in cattle in veterinary practice. This case demonstrated that periodontal surgical correction of facial gingival recession with a subepithelial graft may be performed prior to initiating orthodontic treatment. Both mitochondrion-dependent and endoplasmic reticulum stress-induced apoptotic pathways were also activated in the hearts of doxorubicin-treated mice as reflected by decreased Bcl-2/Bcl-(XL) and elevated Bax/Bad, p53/Apaf-1, endoplasmic reticulum glucose-related protein 78, C/EBP homologous protein, cytochrome c release from mitochondria, caspases-9/-3 cleavage, and cardiomyocyte apoptosis.

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Here we show that in Sweet potato mild mottle virus (SPMMV, type member of the Ipomovirus genus, family Potyviridae), the role of silencing suppressor is played by the P1 protein (the largest serine protease among all known potyvirids) despite the presence in its genome of an HC-Pro protein, which, in potyviruses, acts as the suppressor. This defect predisposes to exaggerated hypoxic pulmonary hypertension already during childhood and may contribute to premature cardiovascular disease in the systemic cozaar drug user reviews circulation later in life. In the present paper, the gelation properties of plasma and its two major fractions (serum and albumin) have been studied at pH 4.5, 6.0 and 7.5. The CTs should be taken into account for the classification of the prognosis of critically ill patients. Double labeling with the antibody against phenyl ethanolamine-N-methyltransferase, which marks adrenaline-producing chromaffin cells, revealed that only a few of the P2Y2-immunoreactive cells were adrenaline producing at embryonic day E16, the vast majority being noradrenaline-containing cells. Affinity prediction on A1 adenosine receptor agonists: the chemometric approach. All study sites conducted this study in compliance with HIPAA requirements. In the upper dermis, collagenolysis and phagocytosis of degenerated collagen fragments were observed. High frequency asynchronous magnetic bead rotation for improved biosensors. Cephalometric pattern of Jewish East European adolescents with clinically acceptable occlusion.

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