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Alvastin (Atorvastatin)
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Alvastin

Alvastin is a lipid-lowering drug included in the statin class of medications. It ultimately reduces the risk of cardiovascular disease. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase, which catalyzes the conversion of HMG-CoA to mevalonic acid.

Other names for this medication:
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Also known as: Atorvastatin

Description

Alvastin (atorvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

Alvastin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Alvastin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors such as genetically high cholesterol.

Alvastin is for use in adults and children who are at least 10 years old.

Dosage

Take Alvastin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Alvastin is usually taken once a day, with or without food. Take the medicine at the same time each day.

Do not break an Alvastin tablet before taking it, unless your doctor has told you to.

You may need to stop using this medicine for a short time if you have:

uncontrolled seizures; an electrolyte imbalance (such as high or low potassium levels in your blood); severely low blood pressure; a severe infection or illness; or surgery or a medical emergency.

It may take up to 2 weeks before your cholesterol levels improve, and you may need frequent blood test. Even if you have no symptoms, tests can help your doctor determine if Alvastin is effective.

Alvastin is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Alvastin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alvastin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid eating foods that are high in fat or cholesterol. Alvastin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

Grapefruit and grapefruit juice may interact with atorvastatin and lead to unwanted side effects. Avoid drinking more than 1 liter of grapefruit juice per day while taking this medicine.

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Notably, substrate release can occur in the absence of a lid, and lid closure can occur without substrate release. Sodium succinate therapy in multiple sclerosis and other neurological disorders. The diagnostic approach, differential diagnosis and treatment options are discussed emphasizing the characteristics of cutaneous lesions in immunosuppressed transplant recipients. Typhimurium virulence plasmid, pSTV, did not influence these results. Regeneration of the extremities of the adult Axolotl, at the expense of embryonal grafts. Cisplatin modulates B-cell translocation gene 2 to attenuate cell proliferation of prostate carcinoma cells in both p53-dependent and p53-independent pathways. ABL mutation was detected by nested reverse transcription polymerase chain reaction (PCR) followed by direct sequencing. Northern blot analysis and nuclear run-off assays revealed maximum DOR mRNA level and transcription rate, respectively, during the G0/G1 phase of NG108-15 cells. Granulosa cell tumor of the ovary with Sertoli-Leydig cell tumor components (gynandroblastoma).

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Synthesis and characterization of two (111)In-labeled DTPA-peptide conjugates. Supernatants prepared by incubating Contortrix venom with fibrinogen, which cleaves the B peptide, were also chemotactic, whereas no activity was present in supernatants from Arvin venom, which cleaves peptides A, AP and AY. Surgeons and residents are at increased risk of exposure to blood-borne pathogens owing to percutaneous injury (PI) and contamination. No MAV-binding proteins were detected from the nonvector aphid, Rhopalosiphum maidis, although MAV4 anti-ID did react with four proteins from R. Here, I examine recent data from expression and proteomic studies that suggest that cells make slightly different ribosomes under different growth conditions, and discuss genetic evidence that such differences are functional.

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The present study further suggests that the anomaly of insulin removal observed in perfused livers of ob/ob mice might be secondary to hyperinsulinemia, since it was partly corrected upon artificially decreasing the circulating levels of insulin (e.g. Applying an equity lens approach to evaluate the effects of health interventions. Recombinant plasmids carrying the phi 80-PL promoter and nut-equivalent site of phi 80 are lethal to the Escherichia coli host cell, but can be stably maintained in the presence of the phi 80-cI repressor. In smoking cessation trials, placebo response rates are reported to be rather low, and they are lowest when compared to the placebo response rates of treatment of other addictions. Seventy-five patients (Group A) had rectal excision with closure of the pelvic peritoneum and packing of the pelvic space via an open perineal wound. Both activities use ADP much more effectively than ATP and are inhibited by stem-loop structures. The model predicts increased plasma Pb levels for a given whole-blood Pb value as pregnancy advances for whole-blood Pb levels greater than approximately 110 microg/L, but not for blood Pb levels less than 100 microg/L. In particular, the study was intended to answer the question of whether the results of FDG-PET correlate with those found in intraoperatively removed biopsy specimens (microbiology, histology) and what value this method of investigation has relative to computed tomography (CT) and magnetic resonance imaging (MRI).

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Selective reporting of randomised controlled trials (RCTs) is a common problem. LPS had marginal effects at the concentrations present in the recombinant protein preparations and the TcCRT antiangiogenic effects were largely inhibited by specific polyclonal antibodies, thus, reinforcing the fact that the observed TcCRT effects can be attributed to the parasite-derived molecule and not to the endotoxin. Effects of duct reconstruction and estrogen treatment on endocrine and exocrine functions of fibrotic pancreas caused by ligation of the pancreatic duct in dogs. The waveform analysis performed by the program system is validated in a statistical comparison between manually and automatically computed values. Twenty-nine patients with rectal carcinoma were staged with EUS and body coil MRI and then underwent radical surgery. Complementary strategies aimed at selective killing of infected cells are described. Combined hemodynamic-ultrasonic method for studying left ventricular wall stress: comparison with angiography. Novel polyhedral gold nanoparticles: green synthesis, optimization and characterization by environmental isolate of Acinetobacter sp. Here, we review the nature of stimuli that modulate p120ctn function and are translated as serine/threonine and tyrosine phosphorylation events at this multisite substrate for a variety of protein kinases.

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This review presents a summary of state-of-the-art technologies for genomic sequencing and describes technologies that may be candidates for the next generation of DNA sequencing instruments. Comments on the Affordable Care Act and the future of clinical medicine. TIDA neuronal activity was quantified in diestrous female rats to determine whether OFQ/N stimulates prolactin release by inhibiting TIDA neurons. Effect of monensin on the performance and nitrogen utilization of lactating dairy cows consuming fresh forage. Factors associated with clinical trial screening failures in gynecologic oncology. Vascular smooth muscle cells are of major interest for the evaluation of atherosclerotic processes. In all fields so examined, the thin-profile crystallites that were properly oriented with respect to the axis of tilt exhibited a different width dimension in each of the two micrographs. Attempts to inhibit the serum enzyme in vitro using high concentrations of thyroxine and tri-iodothyronine were unsuccessful. Oral lichen planus: clinical and histological evaluation in an open trial using a low molecular weight heparinoid (sulodexide). Finally, 3D model structure of WbCTI was designed using computer simulations which further emphasize the roles of L63 and R64 residues for dual inhibitory characteristics of WbCTI.

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In yeast two-hybrid assays, Pex10p and Pex11pbeta interacted only with full-length Pex19p. Consequently, we have measured changes in the rate of energy consumption of running human subjects produced by artificial alterations in limb inertial properties. Furthermore, carcinogen-transformed rodent cells display aberrations in the expression of various endogenous retrovirus-related sequences. DWI was performed immediately before and within 48 hours after unprotected or protected CAS. Syndromes of the paramedic pontine reticular formation, medial longitudinal fascicules and one-and-a-half syndrome are caused by disease of the pons.

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Vehicle-injected wild type (WT) mice and D3(-/-) animals were used as controls and submitted to the same experimental procedure. Occlusion of left common iliac vein by a distended urinary bladder in a male with paraplegia due to spinal cord injury. Corticosteroids have been a cornerstone of immunosuppression for four decades despite their adverse side effects. To attain the objective function, several commercial UHT milk were analyzed and for the computer search the minimization of hydroxy methyl furfural (HMF) formation was considered and also including constraints for protease and lipase inactivation. The chemical biology of HNO has been identified as related to, but unique from, that of its redox congener nitric oxide.

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Thus, TAA decreased significantly in GG (high-expression genotype) homozygotes, whereas ICAM-1 levels were reduced in A allele carriers. Planning ability in adults with attention-deficit/hyperactivity disorder. These results suggest that TGB is unlikely to cause visual field defects in humans. No single diagnostic criterion is sufficiently sensitive and specific xanax pills and doses to be pathognomonic. Grants for Foreign Graduate Students to Attend AAAS Annual Meeting. Dissolution rates of high energy sulfathiazole--povidone coprecipitates II: characterization of form of drug controlling its dissolution rate via solubility studies. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. Productive inventory and case/agreement contingencies: a methodological note on Rispoli (1999).

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