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Alzine (Cetirizine)
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Alzine

Alzine is an antihistamine used to treat seasonal allergies and hives. It is available over the counter, though children under six with hives will still need a prescription. A generic version of Zyrtec is also available over the counter, sold as Alzine.

Other names for this medication:
Aaptol, Alerbloc, Cetnac, Cetramac, Cetriz, Cetven, Cetzine, Coldec, Confree, Enecet, Fastcet, Flamoset, Formicet, Lemohist, Okacet, Olcit, Onacold, Relent, Semcold, Setri, Sizon, Tecol, Tercuf, Urtizine, Vencare, Zyncet

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Also known as: Cetirizine

Description

Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Dosage

Alzine can be taken in tablets (5 mg, 10 mg), syrup (1ml), chewable tablets (5 mg, 10 mg). You should take it by mouth. It would be better to take Alzine every day at the same time. It is better to take Alzine once a day (with or without meals). Alzine of 10 mg works for 24 hours. Alzine can be given to children of 2 years and infants of 6 months. Elderly people who are over 60 years should use Alzine lowest dose. If you want to achieve most effective results do not stop taking Alzine suddenly.

Overdose

Seek emergency medical attention if you think you have used too much of Alzine-D.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

Side effects

The most common side effects associated with Alzine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Alzine if you are allergic to Alzine components. Try to be careful with Alzine if you're pregnant or you plan to have a baby, or you are a nursing mother. Alzine can harm your baby. Try to be careful with Alzine usage in case of having kidney or liver disease. Try to be careful with Alzine usage in case of taking cough, cold or allergy medication, depression medication (paroxetine as Paxil, nortriptyline as Pamelor, amitriptyline as Elavil; sertraline as Zoloft, fluoxetine as Prozac, doxepin as Sinequan), medicines for anxiety or sleep (triazolam as Halcion, chlordiazepoxide as Librium, alprazolam as Xanax, diazepam as Valium, temazepam as Restoril). Try to avoid machine driving. Alzine can be given to children of 2 years and infants of 6 months. Elderly people who are over 60 years should use Alzine lowest dose. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Do not stop taking Alzine suddenly.

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To elucidate the role of GSH in regulation of AP-1, NF-kappaB, and VCAM-1 expression, we employed l-buthionine (S,R)-sulfoximine (BSO), a specific gamma-glutamylcysteine synthetase (gamma-GCS) inhibitor, to block intracellular GSH synthesis. These results suggest that patients with chronic posttraumatic osteomyelitis do not function significantly below that of the normal population following eradication of their infections. We applied this technique and successfully shifted the switching threshold voltages of NMOS-based inverters and improved their noise margin, in both depletion and enhancement modes. These antibodies were directed to the conserved stem region of HA and were also elicited in nonhuman primates. The hypothesis was confirmed that incarcerated men with a diagnosis of pathological gambling are characterized by psychopathic personality disorders, alcohol problems and criminality.

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The catalytic enzyme activity of its Escherichia coli DCP counter part can be inhibited by the antihypertensive drug captopril, suggesting that this class of enzymes constitutes a novel target for drugs and vaccines. The BRCT domains of BRCA1 bind phosphorylated protein through a pSXXF consensus recognition motif. In dairy cattle, histopathology of the outer hind claws with overgrown sole revealed arteriosclerosis of blood vessels at the ulcer site in the sole. Quality of life aspects in patients operated for low rectal cancer. This conclusion is supported by studies in both the field and in the laboratory. Negative results were observed in 6 of the isolates: Panama (4), Honduras (1), and Brazil (1). A health and nutritional evaluation of changes in agriculture in the past quarter century in British Columbia: implications for food security.

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