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Amitwix (Amitriptyline)

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Amitwix is an antidepressant medication that is sometimes prescribed off-label to manage chronic back pain. It is one of the drugs in a class of drugs known as tricyclic antidepressants. Amitwix is not a narcotic (opioid) drug, and there is not usually an addiction risk with the medication.

Other names for this medication:
Amiclozor, Amicon, Amidez, Amiline, Amitar, Amitin, Amitop, Amitrac, Amitriptyline, Amitrix, Amitryn, Amitryptyline, Amitwix, Amiwel, Amixide, Amline, Amoten, Amtipax, Axtrip, Chlotrip, Cotrip, Eliwel, Emotrip, Endep, Latiln, Librodep, Limbitrol, Limbival, Lodep, Maxitrip, Mitrip, Nextrip, Normaline, Psycomer, Sarotena, Sereval, Teedep, Triplent, Tryptomec, Typlin, Typteez

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Also known as: Amitriptyline


Amitwix (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amitwix is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitwix dosage information


If you overdose Amitwix and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitwix overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitwix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with amitriptyline.

Avoid driving or hazardous activity until you know how Amitwix will affect you. Your reactions could be impaired.

Avoid exposure to sunlight or tanning beds. Amitriptyline can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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Genetics of chemical induction of conjugation in Paramecium aurella. Coexistence of substance P and calcitonin gene-related peptide (CGRP) is demonstrated in nerve fibres of the guinea pig carotid body, which originate in the petrosal and jugular ganglia. Preparation of morphine-6-3H and its isotopic stability in man and in rat. To report a case of Shewannela putrefaciens endophthalmitis after penetrating keratoplasty. Coping behavior in women with miscarriage or spontaneous abortion and recurrent spontaneous abortion. Ethylation interference footprinting of two XerD catalytic mutant proteins suggests that the conserved domain II arginine from the integrase family RHRY tetrad may make direct contact with the scissile phosphate. The removal rates for bleeding and pain were 4.9 and 4.8, the removal rates for non medical reasons were 3.7 and 4.9 respectively. Interaction of dietary aflatoxin with some vitamin deficiencies. Differences in multiple segment tremor dynamics between young and elderly persons. The difficulty of each of the school mathematics task was also rated on a 4-point scale.

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Preparation of the myristoylated and nonmyristoylated form of recombinant recoverin in E. For the assessment, focus is set on the early stage of the brownfield redevelopment process, which is characterized by limited data availability and by flexibility in land use planning and development scope. Between July 2008 and December 2009, 55 patients underwent SILS cholecystectomy by two experienced general surgeons at a single institution. He was successfully treated with a 3-vessel custom-made fenestrated stent graft to the renal and the superior mesenteric arteries. The movement of two distinct and characteristic swelling boundaries was measured directly using an optical microscope.

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