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With 2643 records of disease-associated CR events curated from 1172 original studies, dbCRID is a comprehensive and dynamic resource useful for studying DNA breakage and repair mechanisms, and for analyzing the genetic basis of human tumor and non-tumor diseases. A systematic examination of brain volumetric abnormalities in recent-onset schizophrenia using voxel-based, surface-based and region-of-interest-based morphometric analyses. In contrast to the training group, the placebo control group did not show a difference. In lungs from transplant patients with severe obliterative bronchiolitis, vascular endothelium, in addition to expressing class I, now consistently expressed class II. Direct invasion of HCC with necrotic tissue to the pleura through the diaphragm appeared to have caused the respiratory failure. Remarks on the apparently primary arteriopathies of the large arteries of the extremities. Telomere lengths were very heterogeneous, but specific chromosomes of bone marrow cells and skin fibroblasts from individual mice had similar telomere lengths. These findings indicated for the first time that the novel helix-loop-helix type transcription factor (scleraxis) mRNA is expressed in osteoblasts and its expression is regulated by TGF beta. Enhancing the Motivation for Rural Career: The Collaboration between the Local Government and Medical School.
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To facilitate clinical application of this electrophysiologic test, a detailed description of modified LEMG techniques is presented. Concerning certain errors in the reading of intraoral roentgenophotographs. A blind trial of two aerosol sprays in the exposure treatment of burns. Mental health services for patients with a major depressive disorder are commonly delivered by primary care. Growth hormone and insulin studies in atrophy caused by nervous system diseases.
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No significant difference in infection rates was demonstrated between the two groups. An investigation of the factors influencing serum pepsinogen levels--sex, age, smoking, drinking. Thus, in addition to blockade in the paraventricular hypothalamic nucleus, c-fos mRNA induction in the lesioned animals was abolished in the bed nucleus of the stria terminalis, especially its anterior medial and ventral aspects, the septohypothalamic nucleus, and the anteroventral preoptic area, compared with unoperated and sham-operated rats. An injectable material which hardened in situ to form a carbonated hydroxyapatite, Norian SRS (Norian Corp., Cupertino, USA), was used as the only treatment of unstable distal radial fractures in six patients. These phase shifts must be accurately calibrated and can be distorted by geometric effects, especially when spherical components with high curvature are tested. Mediastinal tumors can reach a huge size and give rise to serious surgical and oncological problems. The immunogenicity of therapeutic Abs is a concern as anti-drug Abs may impact negatively on the pharmacodynamics and safety profile of Ab drugs. Analytical ultracentrifugation and circular dichroism revealed, respectively, that the histidine-tagged enzyme is in tetrameric form with a molecular weight of 220 kDa and contains predominantly alpha-helical structure.
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Clinical evaluation of two posterior composite resins retained with bonding agents. A case presentation has been made to illustrate the clinical significance of this problem. Impact of design considerations of nonclinical and clinical results are presented in detail. Few-photon imaging at 1550 nm using a low-timing-jitter superconducting nanowire single-photon detector. Self-reported recent physical activity was related to objective exercise monitoring. Arsenic trioxide (As2O3) is highly efficacious in acute promyelocytic leukemia (APL). The influences of zinc in a meal and usual zinc intake on zinc retention and turnover were investigated in 7-wk-old male rats fed diets containing 12-151 mg Zn/kg for 3 wk before and after consuming a 65Zn-labeled meal containing ZnCl2. The correlation was constructed and validated with experimentally obtained mean microsphere diameters prepared at different stirring speeds.
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Genomic footprinting of Drosophila embryo nuclei by linker tag selection LM-PCR. Viral Etiology of Chronic Obstructive Pulmonary Disease Exacerbations during the A/H1N1pdm09 Pandemic and Postpandemic Period. Herein, we report results from a series of 15 patients treated with ruthenium-106 (Ru-106) plaque brachytherapy using PS pretreatment modeling for plaque localization and dosimetry. A patient with non-small cell lung carcinoma experienced a minor response, and a patient with hepatocellular carcinoma had stable disease lasting 11 months. The absence of cross-reaction of antibodies with the nerve growth factor and kallikrein (biologically active substances contained in the submandibular gland granular ducts) was established. We employed Reverse Phase Protein Microarrays to identify aberrantly activated proteins in 118 pediatric B-cell precursor (BCP)-ALL patients.
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The goal of this study was to examine the potential of MRI-based trabecular bone structure parameters to monitor effects of alendronate in humans in vivo, and to compare the results to HR-pQCT and DXA measurements. The value of transcranial Doppler sonography is demonstrated in two infants with an elevation of intracranial pressure (ICP). funestus material from Zambia (ZamF), and to investigate the repellent effects of two formulations of C8910 against these strains. HER2-targeted therapy has moved beyond trastuzumab to include other monoclonals targeting the cell surface, receptor tyrosine kinase inhibitors of HER2, and antibody-drug conjugates. The lateral and deep margins were free of cancerous cells based on histopathology study. These findings do not appear to vary according to geographic region or race/ethnicity. Is activated C3 a premier factor of DIC development in septic shock?.
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Plasminogen activator inhibitor-1 and the risk of Type 2 diabetes mellitus in American Indians: the Strong Heart Study. Molecular epidemiological characterization of poultry red mite, Dermanyssus gallinae, in Japan. Currently, theory and practice of VRA of soil herbicides is developed within the research program IJKakker in close cooperation with pioneering farmers in The Netherlands. Reverse-micelle model: pH, electromagnetic field and inhibitor enzyme interaction. TCRzeta mRNA splice variant forms observed in the peripheral blood T cells from systemic lupus erythematosus patients.
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Gennet, Center of Medical Genetics and Reproductive Medicine, Prague. In addition, A and B substances in secretor saliva could also be measured 3- to 10-fold and 100- to 1,000-fold more sensitively, respectively, by the present method than by the hemagglutination inhibition method. In addition, the behaviour of DF in this time period exhibited characteristic kinetics indicative of the chemical being tested. Can lateral asymmetries in attention explain interfield differences in visual perception?. Further studies are being performed to identify all the discriminant biomarkers of interest and to test our potential markers in a new cohort of animals. The significant and consistently higher serum values of these vitamins among salad consumers suggest that they are being well absorbed from salad. showed oral antihyperuricemic activity in potassium oxonate- and uric acid-induced hyperuricemic rats.
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The levels of the stem cell markers Stro-1 and alkaline phosphatase and the neural progenitor marker nestin were also examined throughout the differentiation process. There are, however, relatively few reports on such studies with double chain monellin. Coating 5micron particles with carbon and metals for lung clearance studies. In this study, we took a different approach by depleting endogenous PrPC using specific interfering RNA technique and compared the depleting and overproducing effects of PrPC on STS-induced apoptosis in neuro-2a (N2a) cells. Then, cellular morphology, viability, cell cycle, Ki67expression, and PI3K/MAPK activation of RPE cells treated with PSPA were determined. Development of a clinical algorithm to prioritise HIV testing of hospitalised paediatric patients in a low resource moderate prevalence setting. Role of dietary restriction in Haemoccult screening for colorectal cancer. Effects of cyclosporine and tacrolimus on the oxidative stress in cultured mesangial cells.
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Long-term outcomes of the Project EX classroom-based program are promising for adolescent prevention and possibly cessation in Spain. FOB is diagnostically useful in the evaluation of some BMT patients with pulmonary complications and often influences therapy, although no impact on survival was clearly demonstrated. Patient-tailored treatments for breast cancer are based on histological and immunohistochemical (IHC) subtypes. In 9 of 11 patients with complete proximal occlusion, the distal portion of the cerebral artery was visible as an area of high signal intensity on FLAIR images. In particular, immunohistochemical analyses have shown that the nuclear expression of the RelA subunit in primary prostate tumors is associated with poor clinical outcome. Alkylating agents are a group of compounds that have a cytotoxic effect due to their ability to form adducts with DNA. By conventional Southern blot hybridisation, no junction fragments were detected in 27 unrelated patients with Duchenne (DMD) or Becker (BMD) muscular dystrophy, who had 20 deletions and seven duplications in the dystrophin gene. With refinement of technique and use of robotic assistant, the shortcomings of laparoscopic approach can be further reduced. Bioassay of rainbow trout (Oncorhynchus mykiss) pigmentation using ancho chili (Capsicum annuum) extracts. Drainage obstruction of the contrast medium was observed in 24 cases.
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This diagnostic certainty makes the decision to remove such a kidney a philosophical one. Together, the present results suggest that empathy seems to rely on neural processes that are (partially) functionally equivalent to those engaged by first-hand emotion experiences. Recent studies demonstrate that hospital-based systems can improve medical care and education of hospitalized HF patients and accelerate use of evidence-based, guideline-recommended therapies by administering them before hospital discharge. To overcome this problem, immortal HeLa cell line express telomerase, an enzyme that prevents telomere shortening. A 23-year-old heart and lung transplant patient ingested 375 mg of tacrolimus. To analyse the content of a series of Feldenkrais Method balance classes to gain an understanding of how the results in these studies may have been achieved and the principles through which the method may be effective. Using this method only 172 amongst the former 268 BVD virus carriers were found. The dorsal branch (tom-d) projects bilaterally to a complex pattern of terminal fields, including the medial terminal field in V, the central terminal field in the dorsomedial forebrain (Dm), the caudal part of the lateral terminal field in the dorsoposterior telencephalon (Dp), and, finally, a hypothalamic terminal field at the lateral edge of the posterior nucleus tuberis.
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Calpain-2 Inhibitor Therapy Reduces Murine Colitis and Colitis-associated Cancer. Pneumothorax after pneumonectomy: surgery with successful double lobe ventilation. Until recently, therapeutic strategies for the management of these sequelae have been symptomatic rather than preventive. Male transgenic mice overexpressing TGF alpha have elevated serum estradiol (E2) levels and they exhibit feminization of many nonreproductive actions, suggesting that either TGF alpha and/or E2, or both, participate in the control of some nonreproductive behavior. Tacrolimus and methotrexate for the prophylaxis of acute graft-versus-host disease in allogeneic bone marrow transplantation in patients with hematologic malignancies. Detection of a Protein in Human Platelet Membranes which Binds Low-density Lipoproteins. Analysis of different breast cancer subtypes showed distinct correlations of each cluster with clinical outcome. In the medial and anterior parvicellular subnuclei, the double-labelled neurones of treated rats significantly outnumbered those of controls. An in vitro investigation of developmental defects of enamel under wet and dry conditions. We further hypothesized that a unique pattern of gene expression was induced by cell-detachment of anoikis-resistant cell lines, and cDNA microarray analysis was performed using a panel of anoikis-resistant oral cancer cell lines grown under attached and detached growth conditions.